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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q02543 RPL18A Large ribosomal subunit protein eL20 … Homo sapiens (Human) 176 aa

Protein Details: Q02543 (RPL18A)

Protein Information
Accession Q02543
Protein Names Large ribosomal subunit protein eL20 (60S ribosomal protein L18a)
Gene Symbol RPL18A
Organism Homo sapiens (Human)
Length 176 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.659
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
27
LNCaP cells
Specificity: 0.659
27/46 (58.7%)
10
HAP1 cells
Specificity: 0.244
10/10 (100.0%)
4
293T cells
Specificity: 0.098
4/10 (40.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKASGTLREY11KVVGRCLPTP21KCHTPPLYRM31RIFAPNHVVA41KSRFWYFVSQ
51-10051LKKMKKSSGE61IVYCGQVFEK71SPLRVKNFGI81WLRYDSRSGT91HNMYREYRDL
101-150101TTAGAVTQCY111RDMGARHRAR121AHSIQIMKVE131EIAASKCRRP141AVKQFHDSKI
151-176151KFPLPHRVLR161RQHKPRFTTK171RPNTFF
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
64 Prediction (Medium) - -
109 CYSMODDB SWISSPALM DBPTM Prediction (High) Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A -
137 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
29 R → C 0.002545 SNP Missense Mutation GBM
43 R → C 0.002506 SNP Missense Mutation COAD
63 Y → C 0.001887 SNP Missense Mutation UCEC
83 R → C 0.002506 SNP Missense Mutation COAD
83 R → C 0.001969 SNP Missense Mutation LGG
166 R → C 0.001014 SNP Missense Mutation BRCA
109* C → ? 0.005618 SNP Nonsense Mutation PAAD