Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q04446 GBE1 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher … Homo sapiens (Human) 702 aa

Protein Details: Q04446 (GBE1)

Protein Information
Accession Q04446
Protein Names 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)
Gene Symbol GBE1
Organism Homo sapiens (Human)
Length 702 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
5
LNCaP cells
Specificity: 0.500
5/46 (10.9%)
4
PC3 cells
Specificity: 0.400
4/4 (100.0%)
1
Liver membrane
Specificity: 0.100
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAPMTPAAR11PEDYEAALNA21ALADVPELAR31LLEIDPYLKP41YAVDFQRRYK
51-10051QFSQILKNIG61ENEGGIDKFS71RGYESFGVHR81CADGGLYCKE91WAPGAEGVFL
101-150101TGDFNGWNPF111SYPYKKLDYG121KWELYIPPKQ131NKSVLVPHGS141KLKVVITSKS
151-200151GEILYRISPW161AKYVVREGDN171VNYDWIHWDP181EHSYEFKHSR191PKKPRSLRIY
201-250201ESHVGISSHE211GKVASYKHFT221CNVLPRIKGL231GYNCIQLMAI241MEHAYYASFG
251-300251YQITSFFAAS261SRYGTPEELQ271ELVDTAHSMG281IIVLLDVVHS291HASKNSADGL
301-350301NMFDGTDSCY311FHSGPRGTHD321LWDSRLFAYS331SWEILRFLLS341NIRWWLEEYR
351-400351FDGFRFDGVT361SMLYHHHGVG371QGFSGDYSEY381FGLQVDEDAL391TYLMLANHLV
401-450401HTLCPDSITI411AEDVSGMPAL421CSPISQGGGG431FDYRLAMAIP441DKWIQLLKEF
451-500451KDEDWNMGDI461VYTLTNRRYL471EKCIAYAESH481DQALVGDKSL491AFWLMDAEMY
501-550501TNMSVLTPFT511PVIDRGIQLH521KMIRLITHGL531GGEGYLNFMG541NEFGHPEWLD
551-600551FPRKGNNESY561HYARRQFHLT571DDDLLRYKFL581NNFDRDMNRL591EERYGWLAAP
601-650601QAYVSEKHEG611NKIIAFERAG621LLFIFNFHPS631KSYTDYRVGT641ALPGKFKIVL
651-700651DSDAAEYGGH661QRLDHSTDFF671SEAFEHNGRP681YSLLVYIPSR691VALILQNVDL
701-702701PN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
221 Prediction (High) - -
234 Prediction (Low) - -
421 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
72 G → C 0.003460 SNP Missense Mutation CESC
114 Y → C 0.001764 SNP Missense Mutation LUAD
156 R → C 0.002141 SNP Missense Mutation SKCM
166 R → C 0.002141 SNP Missense Mutation SKCM
202 S → C 0.001014 SNP Missense Mutation BRCA
355 R → C 0.002506 SNP Missense Mutation COAD
355 R → C 0.002141 SNP Missense Mutation SKCM
576 R → C 0.004283 SNP Missense Mutation SKCM
679 R → C 0.002288 SNP Missense Mutation STAD