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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q04828 AKR1C1; DDH; DDH1 Aldo-keto reductase family 1 member … Homo sapiens (Human) 323 aa

Protein Details: Q04828 (AKR1C1)

Protein Information
Accession Q04828
Protein Names Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.210) (EC 1.1.1.357) (EC 1.1.1.51) (EC 1.1.1.53) (EC 1.1.1.62) (EC 1.3.1.20) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1) (DD1) (High-affinity hepatic bile acid-binding protein) (HBAB)
Gene Symbol AKR1C1; DDH; DDH1
Organism Homo sapiens (Human)
Length 323 aa
Isoforms No isoforms
Related PMIDs 26876311
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Prefrontal cortex
Specificity: 1.000
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDSKYQCVKL11NDGHFMPVLG21FGTYAPAEVP31KSKALEATKL41AIEAGFRHID
51-10051SAHLYNNEEQ61VGLAIRSKIA71DGSVKREDIF81YTSKLWCNSH91RPELVRPALE
101-150101RSLKNLQLDY111VDLYLIHFPV121SVKPGEEVIP131KDENGKILFD141TVDLCATWEA
151-200151VEKCKDAGLA161KSIGVSNFNR171RQLEMILNKP181GLKYKPVCNQ191VECHPYFNQR
201-250201KLLDFCKSKD211IVLVAYSALG221SHREEPWVDP231NSPVLLEDPV241LCALAKKHKR
251-300251TPALIALRYQ261LQRGVVVLAK271SYNEQRIRQN281VQVFEFQLTS291EEMKAIDGLN
301-323301RNVRYLTLDI311FAGPPNYPFS321DEY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
7 Prediction (Low) - -
145 Prediction (Medium) - -
206 CYSMODDB SWISSPALM DBPTM Prediction (Low) Aldo/keto reductase family -
242 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
55 Y → C 0.002506 SNP Missense Mutation COAD
188 C → G 0.002294 SNP Missense Mutation OV
188 C → R 0.002545 SNP Missense Mutation GBM
216 Y → C 0.001764 SNP Missense Mutation LUAD
263 R → C 0.001887 SNP Missense Mutation UCEC
276 R → C 0.002506 SNP Missense Mutation COAD