Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q04917 | YWHAH; YWHA1 | 14-3-3 protein eta (Protein AS1) | Homo sapiens (Human) | 246 aa |
Protein Details: Q04917 (YWHAH)
Protein Information
| Accession | Q04917 |
|---|---|
| Protein Names | 14-3-3 protein eta (Protein AS1) |
| Gene Symbol | YWHAH; YWHA1 |
| Organism | Homo sapiens (Human) |
| Length | 246 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29733200 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.364
12/46 (26.1%)
6
HAP1 cells
Specificity: 0.182
6/10 (60.0%)
4
Jurkat T cells
Specificity: 0.121
4/25 (16.0%)
4
293T cells
Specificity: 0.121
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.121
4/4 (100.0%)
3
PC3 cells
Specificity: 0.091
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGDREQLLQR11ARLAEQAERY21DDMASAMKAV31TELNEPLSNE41DRNLLSVAYK
51-10051NVVGARRSSW61RVISSIEQKT71MADGNEKKLE81KVKAYREKIE91KELETVCNDV
101-150101LSLLDKFLIK111NCNDFQYESK121VFYLKMKGDY131YRYLAEVASG141EKKNSVVEAS
151-200151EAAYKEAFEI161SKEQMQPTHP171IRLGLALNFS181VFYYEIQNAP191EQACLLAKQA
201-246201FDDAIAELDT211LNEDSYKDST221LIMQLLRDNL231TLWTSDQQDE241EAGEGN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 97 | Prediction (High) | - | - |
| 112 | Prediction (High) | - | - |
| 194 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 112 | C → G | 0.001887 | SNP | Missense Mutation | UCEC |
| 112 | C → delins* | 0.001887 | INS | Nonsense Mutation | UCEC |