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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q05144 Rac2 Ras-related C3 botulinum toxin substrate … Mus musculus (Mouse) 192 aa

Protein Details: Q05144 (Rac2)

Protein Information
AccessionQ05144
Protein NamesRas-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (Protein EN-7) (p21-Rac2)
Gene SymbolRac2
OrganismMus musculus (Mouse)
Length192 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQAIKCVVVG11DGAVGKTCLL21ISYTTNAFPG31EYIPTVFDNY41SANVMVDSKP
51-10051VNLGLWDTAG61QEDYDRLRPL71SYPQTDVFLI81CFSLVSPASY91ENVRAKWFPE
101-150101VRHHCPSTPI111ILVGTKLDLR121DDKDTIEKLK131EKKLAPITYP141QGLALAKDID
151-192151SVKYLECSAL161TQRGLKTVFD171EAIRAVLCPQ181PTRQQKRPCS191LL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase
Brain (34200797)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.09
18 P-loop containing nucleoside triphosphate hydrolase Transforming protein P21 ras signature Small GTPase Small GTPase Rho - -
GPS-Palm: 0.76
Deep-Palm: 0.97
81 - - -
Deep-Palm: 0.95
105 - - -
Deep-Palm: 0.97
157 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.91
Deep-Palm: 0.98
178 - - -
GPS-Palm: 0.93
Deep-Palm: 0.97
189 - - -
GPS-Palm: 0.97
Deep-Palm: 0.03
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
Liver
Specificity: 0.075
3/3 (100.0%)
2
Brain
Specificity: 0.050
2/2 (100.0%)
1
Testis
Specificity: 0.025
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
34
Brain tissue (Mass)
Specificity: 0.850
34/56 (60.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine