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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q06830 PRDX1; PAGA; PAGB; TDPX2 Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer … Homo sapiens (Human) 199 aa

Protein Details: Q06830 (PRDX1)

Protein Information
Accession Q06830
Protein Names Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene Symbol PRDX1; PAGA; PAGB; TDPX2
Organism Homo sapiens (Human)
Length 199 aa
Isoforms No isoforms
Related PMIDs 21076176 25914232 29575903 29733200 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.540
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.540
34/46 (73.9%)
10
HAP1 cells
Specificity: 0.159
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.063
4/25 (16.0%)
4
PC3 cells
Specificity: 0.063
4/4 (100.0%)
4
293T cells
Specificity: 0.063
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.063
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.048
3/3 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSSGNAKIGH11PAPNFKATAV21MPDGQFKDIS31LSDYKGKYVV41FFFYPLDFTF
51-10051VCPTEIIAFS61DRAEEFKKLN71CQVIGASVDS81HFCHLAWVNT91PKKQGGLGPM
101-150101NIPLVSDPKR111TIAQDYGVLK121ADEGISFRGL131FIIDDKGILR141QITVNDLPVG
151-199151RSVDETLRLV161QAFQFTDKHG171EVCPAGWKPG181SDTIKPDVQK191SKEYFSKQK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
71 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) AhpC/TSA family 29575903
83 Experimental CYSMODDB SWISSPALM DBPTM AhpC/TSA family 29575903
173 Experimental CYSMODDB SWISSPALM DBPTM C-terminal domain of 1-Cys peroxiredoxin 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
71 C → Y 0.001887 SNP Missense Mutation UCEC