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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q07065 CKAP4 Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking … Homo sapiens (Human) 602 aa

Protein Details: Q07065 (CKAP4)

Protein Information
Accession Q07065
Protein Names Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene Symbol CKAP4
Organism Homo sapiens (Human)
Length 602 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 24357059 26111759 29575903 29733200 31251020 32651440 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.519
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
41
LNCaP cells
Specificity: 0.519
41/46 (89.1%)
10
HAP1 cells
Specificity: 0.127
10/10 (100.0%)
6
293T cells
Specificity: 0.076
6/10 (60.0%)
5
Jurkat T cells
Specificity: 0.063
5/25 (20.0%)
4
PC3 cells
Specificity: 0.051
4/4 (100.0%)
4
T cells
Specificity: 0.051
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.051
4/4 (100.0%)
2
DU145 cells
Specificity: 0.025
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.025
2/2 (100.0%)
1
HeLa cells
Specificity: 0.013
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPSAKQRGSK11GGHGAASPSE21KGAHPSGGAD31DVAKKPPPAP41QQPPPPPAPH
51-10051PQQHPQQHPQ61NQAHGKGGHR71GGGGGGGKSS81SSSSASAAAA91AAAASSSASC
101-150101SRRLGRALNF111LFYLALVAAA121AFSGWCVHHV131LEEVQQVRRS141HQDFSRQREE
151-200151LGQGLQGVEQ161KVQSLQATFG171TFESILRSSQ181HKQDLTEKAV191KQGESEVSRI
201-250201SEVLQKLQNE211ILKDLSDGIH221VVKDARERDF231TSLENTVEER241LTELTKSIND
251-300251NIAIFTEVQK261RSQKEINDMK271AKVASLEESE281GNKQDLKALK291EAVKEIQTSA
301-350301KSREWDMEAL311RSTLQTMESD321IYTEVRELVS331LKQEQQAFKE341AADTERLALQ
351-400351ALTEKLLRSE361ESVSRLPEEI371RRLEEELRQL381KSDSHGPKED391GGFRHSEAFE
401-450401ALQQKSQGLD411SRLQHVEDGV421LSMQVASARQ431TESLESLLSK441SQEHEQRLAA
451-500451LQGRLEGLGS461SEADQDGLAS471TVRSLGETQL481VLYGDVEELK491RSVGELPSTV
501-550501ESLQKVQEQV511HTLLSQDQAQ521AARLPPQDFL531DRLSSLDNLK541ASVSQVEADL
551-600551KMLRTAVDSL561VAYSVKIETN571ENNLESAKGL581LDDLRNDLDR591LFVKVEKIHE
601-602601KV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
100 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 29575903, 19801377
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
326 R → C 0.002288 SNP Missense Mutation STAD
429 R → C 0.006993 SNP Missense Mutation LAML
454 R → C 0.002545 SNP Missense Mutation GBM
494 G → C 0.002545 SNP Missense Mutation GBM