Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q07812 | BAX | Apoptosis regulator BAX (Bcl-2-like protein … | Homo sapiens (Human) | 192 aa |
Protein Details: Q07812 (BAX)
Protein Information
| Accession | Q07812 |
|---|---|
| Protein Names | Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4) |
| Gene Symbol | BAX |
| Organism | Homo sapiens (Human) |
| Length | 192 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31382980 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDGSGEQPRG11GGPTSSEQIM21KTGALLLQGF31IQDRAGRMGG41EAPELALDPV
51-10051PQDASTKKLS61ECLKRIGDEL71DSNMELQRMI81AAVDTDSPRE91VFFRVAADMF
101-150101SDGNFNWGRV111VALFYFASKL121VLKALCTKVP131ELIRTIMGWT141LDFLRERLLG
151-192151WIQDQGGWDG161LLSYFGTPTW171QTVTIFVAGV181LTASLTIWKK191MG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.92
|
|
| 126 | DBPTM SWISSPALM | Apoptosis regulator proteins Bcl-2 family | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
U937 cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 126 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 126 | C → W | 0.006993 | SNP | Missense Mutation | LAML |
| 139 | W → C | 0.002506 | SNP | Missense Mutation | COAD |