Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q09470 KCNA1 Potassium voltage-gated channel subfamily A … Homo sapiens (Human) 495 aa

Protein Details: Q09470 (KCNA1)

Protein Information
Accession Q09470
Protein Names Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1)
Gene Symbol KCNA1
Organism Homo sapiens (Human)
Length 495 aa
Isoforms No isoforms
Related PMIDs 36430497
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 1.000
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTVMSGENVD11EASAAPGHPQ21DGSYPRQADH31DDHECCERVV41INISGLRFET
51-10051QLKTLAQFPN61TLLGNPKKRM71RYFDPLRNEY81FFDRNRPSFD91AILYYYQSGG
101-150101RLRRPVNVPL111DMFSEEIKFY121ELGEEAMEKF131REDEGFIKEE141ERPLPEKEYQ
151-200151RQVWLLFEYP161ESSGPARVIA171IVSVMVILIS181IVIFCLETLP191ELKDDKDFTG
201-250201TVHRIDNTTV211IYNSNIFTDP221FFIVETLCII231WFSFELVVRF241FACPSKTDFF
251-300251KNIMNFIDIV261AIIPYFITLG271TEIAEQEGNQ281KGEQATSLAI291LRVIRLVRVF
301-350301RIFKLSRHSK311GLQILGQTLK321ASMRELGLLI331FFLFIGVILF341SSAVYFAEAE
351-400351EAESHFSSIP361DAFWWAVVSM371TTVGYGDMYP381VTIGGKIVGS391LCAIAGVLTI
401-450401ALPVPVIVSN411FNYFYHRETE421GEEQAQLLHV431SSPNLASDSD441LSRRSSSTMS
451-495451KSEYMEIEED461MNNSIAHYRQ471VNIRTANCTT481ANQNCVNKSK491LLTDV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
185 Prediction (Low) - -
243 DBPTM SWISSPALM Prediction (High) Ion transport protein -
392 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
35 C → C 0.002288 SNP Silent STAD
36 C → Y 0.001887 SNP Missense Mutation UCEC
69 R → C 0.001014 SNP Missense Mutation BRCA
69 R → C 0.002506 SNP Missense Mutation COAD
71 R → C 0.001969 SNP Missense Mutation HNSC
84 R → C 0.002545 SNP Missense Mutation GBM
149 Y → C 0.001887 SNP Missense Mutation UCEC
239 R → C 0.002506 SNP Missense Mutation COAD
256 F → C 0.002141 SNP Missense Mutation SKCM