Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q12908 | SLC10A2; ASBT; ISBT; NTCP2 | Ileal sodium/bile acid cotransporter (Apical … | Homo sapiens (Human) | 348 aa |
Protein Details: Q12908 (SLC10A2)
Protein Information
| Accession | Q12908 |
|---|---|
| Protein Names | Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2) |
| Gene Symbol | SLC10A2; ASBT; ISBT; NTCP2 |
| Organism | Homo sapiens (Human) |
| Length | 348 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNDPNSCVDN11ATVCSGASCV21VPESNFNNIL31SVVLSTVLTI41LLALVMFSMG
51-10051CNVEIKKFLG61HIKRPWGICV71GFLCQFGIMP81LTGFILSVAF91DILPLQAVVV
101-150101LIIGCCPGGT111ASNILAYWVD121GDMDLSVSMT131TCSTLLALGM141MPLCLLIYTK
151-200151MWVDSGSIVI161PYDNIGTSLV171SLVVPVSIGM181FVNHKWPQKA191KIILKIGSIA
201-250201GAILIVLIAV211VGGILYQSAW221IIAPKLWIIG231TIFPVAGYSL241GFLLARIAGL
251-300251PWYRCRTVAF261ETGMQNTQLC271STIVQLSFTP281EELNVVFTFP291LIYSIFQLAF
301-348301AAIFLGFYVA311YKKCHGKNKA321EIPESKENGT331EPESSFYKAN341GGFQPDEK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 69 | Prediction (Medium) | - | - |
| 105 | Prediction (Low) | - | - |
| 106 | Prediction (Low) | - | - |
| 144 | Prediction (Low) | - | - |
| 255 | Prediction (Medium) | - | - |
| 314 | SWISSPALM Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 51 | C → C | 0.001887 | SNP | Silent | UCEC |
| 69 | C → Y | 0.001764 | SNP | Missense Mutation | LUAD |
| 105 | C → Y | 0.002427 | SNP | Missense Mutation | BLCA |
| 132 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 152 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 166 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 255 | C → W | 0.007299 | SNP | Missense Mutation | READ |
| ? | ? → ? | 0.001764 | SNP | Missense Mutation | LUAD |