Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q12908 | SLC10A2 | Ileal sodium/bile acid cotransporter (Apical … | Homo sapiens (Human) | 348 aa |
Protein Details: Q12908 (SLC10A2)
Protein Information
| Accession | Q12908 |
|---|---|
| Protein Names | Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2) |
| Gene Symbol | SLC10A2 |
| Organism | Homo sapiens (Human) |
| Length | 348 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNDPNSCVDN11ATVCSGASCV21VPESNFNNIL31SVVLSTVLTI41LLALVMFSMG
51-10051CNVEIKKFLG61HIKRPWGICV71GFLCQFGIMP81LTGFILSVAF91DILPLQAVVV
101-150101LIIGCCPGGT111ASNILAYWVD121GDMDLSVSMT131TCSTLLALGM141MPLCLLIYTK
151-200151MWVDSGSIVI161PYDNIGTSLV171SLVVPVSIGM181FVNHKWPQKA191KIILKIGSIA
201-250201GAILIVLIAV211VGGILYQSAW221IIAPKLWIIG231TIFPVAGYSL241GFLLARIAGL
251-300251PWYRCRTVAF261ETGMQNTQLC271STIVQLSFTP281EELNVVFTFP291LIYSIFQLAF
301-348301AAIFLGFYVA311YKKCHGKNKA321EIPESKENGT331EPESSFYKAN341GGFQPDEK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
Deep-Palm: 0.02
|
|
| 14 | - | - | - |
Deep-Palm: 0.02
|
|
| 19 | - | - | - |
Deep-Palm: 0.21
|
|
| 51 | Bile acid:sodium symporter/arsenical resistance protein Acr3 Sodium/solute symporter superfamily Bile acid:sodium symporter | - | - |
Deep-Palm: 0.92
|
|
| 69 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.67
|
|
| 74 | - | - | - |
Deep-Palm: 0.71
|
|
| 105 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.43
|
|
| 106 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.51
|
|
| 132 | - | - | - |
Deep-Palm: 0.81
|
|
| 144 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.88
|
|
| 255 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.91
|
|
| 270 | - | - | - |
Deep-Palm: 0.43
|
|
| 314 | SWISSPALM | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 51 | C → C | 0.001887 | SNP | Silent | UCEC |
| 69 | C → Y | 0.001764 | SNP | Missense Mutation | LUAD |
| 105 | C → Y | 0.002427 | SNP | Missense Mutation | BLCA |
| 132 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 152 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 166 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 255 | C → W | 0.007299 | SNP | Missense Mutation | READ |
| ? | ? → ? | 0.001764 | SNP | Missense Mutation | LUAD |