Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q12999 TSPAN31 Tetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence) Homo sapiens (Human) 210 aa

Protein Details: Q12999 (TSPAN31)

Protein Information
AccessionQ12999
Protein NamesTetraspanin-31 (Tspan-31) (Sarcoma-amplified sequence)
Gene SymbolTSPAN31
OrganismHomo sapiens (Human)
Length210 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVCGGFACSK11NALCALNVVY21MLVSLLLIGV31AAWGKGLGLV41SSIHIIGGVI
51-10051AVGVFLLLIA61VAGLVGAVNH71HQVLLFFYMI81ILGLVFIFQF91VISCSCLAIN
101-150101RSKQTDVINA111SWWVMSNKTR121DELERSFDCC131GLFNLTTLYQ141QDYDFCTAIC
151-200151KSQSPTCQMC161GEKFLKHSDE171ALKILGGVGL181FFSFTEILGV191WLAMRFRNQK
201-210201DPRANPSAFL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 SWISSPALM DBPTM CYSMODDB -
HeLa (37611173)
-
GPS-Palm: 0.97
Deep-Palm: 0.03
8 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.91
Deep-Palm: 0.02
14 - - -
Deep-Palm: 0.95
94 - - -
GPS-Palm: 0.94
Deep-Palm: 0.32
96 - - -
GPS-Palm: 0.93
Deep-Palm: 0.79
129 - - -
GPS-Palm: 0.70
Deep-Palm: 0.74
130 - - -
GPS-Palm: 0.67
Deep-Palm: 0.70
146 - - -
Deep-Palm: 0.05
150 - - -
Deep-Palm: 0.04
157 - - -
Deep-Palm: 0.06
160 - - -
Deep-Palm: 0.39
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
96 C → Y 0.001887 SNP Missense Mutation UCEC
157* C → ? 0.001764 SNP Nonsense Mutation LUAD