Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q13200-2 | PSMD2 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 749 aa |
Protein Details: Q13200-2 (PSMD2)
Protein Information
| Accession | Q13200-2 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2) |
| Gene Symbol | PSMD2 |
| Organism | Homo sapiens (Human) |
| Length | 749 aa |
| Isoforms | |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSMSGEVAKE11WQELDDAEKV21QREPLLTLVK31EIVPYNMAHN41AEHEACDLLM
51-10051EIEQVDMLEK61DIDENAYAKV71CLYLTSCVNY81VPEPENSALL91RCALGVFRKF
101-150101SRFPEALRLA111LMLNDMELVE121DIFTSCKDVV131VQKQMAFMLG141RHGVFLELSE
151-200151DVEEYEDLTE161IMSNVQLNSN171FLALARELDI181MEPKVPDDIY191KTHLENNRFG
201-250201GSGSQVDSAR211MNLASSFVNG221FVNAAFGQDK231LLTDDGNKWL241YKNKDHGMLS
251-300251AAASLGMILL261WDVDGGLTQI271DKYLYSSEDY281IKSGALLACG291IVNSGVRNEC
301-350301DPALALLSDY311VLHNSNTMRL321GSIFGLGLAY331AGSNREDVLT341LLLPVMGDSK
351-400351SSMEVAGVTA361LACGMIAVGS371CNGDVTSTIL381QTIMEKSETE391LKDTYARWLP
401-450401LGLGLNHLGK411GEAIEAILAA421LEVVSEPFRS431FANTLVDVCA441YAGSGNVLKV
451-500451QQLLHICSEH461FDSKEKEEDK471DKKEKKDKDK481KEAPADMGAH491QGVAVLGIAL
501-550501IAMGEEIGAE511MALRTFGHLL521RYGEPTLRRA531VPLALALISV541SNPRLNILDT
551-600551LSKFSHDADP561EVSYNSIFAM571GMVGSGTNNA581RLAAMLRQLA591QYHAKDPNNL
601-650601FMVRLAQGLT611HLGKGTLTLC621PYHSDRQLMS631QVAVAGLLTV641LVSFLDVRNI
651-700651ILGKSHYVLY661GLVAAMQPRM671LVTFDEELRP681LPVSVRVGQA691VDVVGQAGKP
701-749701KTITGFQTHT711TPVLLAHGER721AELATEEFLP731VTPILEGFVI741LRKNPNYDL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 139 | - | - | - |
Deep-Palm: 0.94
|
|
| 205 | - | - | - |
Deep-Palm: 0.14
|
|
| 230 | - | - | - |
Deep-Palm: 0.24
|
|
| 236 | - | - | - |
Deep-Palm: 0.68
|
|
| 251 | - | - | - |
Deep-Palm: 0.91
|
|
| 285 | - | - | - |
Deep-Palm: 0.51
|
|
| 289 | - | - | - |
GPS-Palm: 0.92
|
|
| 448 | - | - | - |
Deep-Palm: 0.97
|
|
| 459 | - | - | - |
Deep-Palm: 0.95
|
|
| 522 | - | - | - |
Deep-Palm: 0.82
|
|
| 530 | - | - | - |
Deep-Palm: 0.96
|
|
| 598 | - | - | - |
Deep-Palm: 0.88
|
|
| 616 | - | - | - |
Deep-Palm: 0.92
|
|
| 779 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 205 | C → C | 0.001887 | SNP | Silent | UCEC |
| 226 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 230 | C → C | 0.002294 | SNP | Silent | OV |
| 251 | C → C | 0.002288 | SNP | Silent | STAD |
| 448 | C → Y | 0.002033 | SNP | Missense Mutation | LUSC |
| 556 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 616 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 763 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 763 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 906 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |