Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q13308-2 | PTK7 | Isoform 2 of Inactive tyrosine-protein … | Homo sapiens (Human) | 1030 aa |
Protein Details: Q13308-2 (PTK7)
Protein Information
| Accession | Q13308-2 |
|---|---|
| Protein Names | Isoform 2 of Inactive tyrosine-protein kinase 7 |
| Gene Symbol | PTK7 |
| Organism | Homo sapiens (Human) |
| Length | 1030 aa |
| Isoforms |
|
| Related PMIDs | 19801377 31251020 32651440 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.870
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
40
LNCaP cells
Specificity: 0.870
40/46 (87.0%)
3
PC3 cells
Specificity: 0.065
3/4 (75.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
Jurkat T cells
Specificity: 0.022
1/25 (4.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGAARGSPAR11PRRLPLLSVL21LLPLLGGTQT31AIVFIKQPSS41QDALQGRRAL
51-10051LRCEVEAPGP61VHVYWLLDGA71PVQDTERRFA81QGSSLSFAAV91DRLQDSGTFQ
101-150101CVARDDVTGE111EARSANASFN121IKWIEAGPVV131LKHPASEAEI141QPQTQVTLRC
151-200151HIDGHPRPTY161QWFRDGTPLS171DGQSNHTVSS181KERNLTLRPA191GPEHSGLYSC
201-250201CAHSAFGQAC211SSQNFTLSIA221DESFARVVLA231PQDVVVARYE241EAMFHCQFSA
251-300251QPPPSLQWLF261EDETPITNRS271RPPHLRRATV281FANGSLLLTQ291VRPRNAGIYR
301-350301CIGQGQRGPP311IILEATLHLA321EIEDMPLFEP331RVFTAGSEER341VTCLPPKGLP
351-400351EPSVWWEHAG361VRLPTHGRVY371QKGHELVLAN381IAESDAGVYT391CHAANLAGQR
401-450401RQDVNITVAT411VPSWLKKPQD421SQLEEGKPGY431LDCLTQATPK441PTVVWYRNQM
451-500451LISEDSRFEV461FKNGTLRINS471VEVYDGTWYR481CMSSTPAGSI491EAQARVQVLD
501-550501GSSLPEWVTD511NAGTLHFARV521TRDDAGNYTC531IASNGPQGQI541RAHVQLTVAV
551-600551FITFKVEPER561TTVYQGHTAL571LQCEAQGDPK581PLIQWKGKDR591ILDPTKLGPR
601-650601MHIFQNGSLV611IHDVAPEDSG621RYTCIAGNSC631NIKHTEAPLY641VVDKPVPEES
651-700651EGPGSPPPYK661MIQTIGLSVG671AAVAYIIAVL681GLMFYCKKRC691KAKRLQKQPE
701-750701GEEPEMECLN711GGPLQNGQPS721AEIQEEVALT731SLGSGPAATN741KRHSTSDKMH
751-800751FPRSSLQPIT761TLGKSEFGEV771FLAKAQGLEE781GVAETLVLVK791SLQSKDEQQQ
801-850801LDFRRELEMF811GKLNHANVVR821LLGLCREAEP831HYMVLEYVDL841GDLKQFLRIS
851-900851KSKDEKLKSQ861PLSTKQKVAL871CTQVALGMEH881LSNNRFVHKD891LAARNCLVSA
901-950901QRQVKVSALG911LSKDVYNSEY921YHFRQAWVPL931RWMSPEAILE941GDFSTKSDVW
951-1000951AFGVLMWEVF961THGEMPHGGQ971ADDEVLADLQ981AGKARLPQPE991GCPSKLYRLM
1001-10301001QRCWALSPKD1011RPSFSEIASA1021LGDSTVDSKP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 686 | Prediction (High) | - | - |
| 690 | Prediction (High) | - | - |
| 896 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 149 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 162 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 201 | C → C | 0.001887 | SNP | Silent | UCEC |
| 340 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 391 | C → S | 0.002294 | SNP | Missense Mutation | OV |
| 429 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 581 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 581 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 613 | C → C | 0.002020 | SNP | Silent | PRAD |
| 925 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 964 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 964 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 990 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |