Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q13554-7 | CAMK2B | Calcium/calmodulin-dependent protein kinase type II … | Homo sapiens (Human) | 449 aa |
Protein Details: Q13554-7 (CAMK2B)
Protein Information
| Accession | Q13554-7 |
|---|---|
| Protein Names | Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17) |
| Gene Symbol | CAMK2B |
| Organism | Homo sapiens (Human) |
| Length | 449 aa |
| Isoforms | |
| Related PMIDs | 31251020 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATTVTCTRF11TDEYQLYEDI21GKGAFSVVRR31CVKLCTGHEY41AAKIINTKKL
51-10051SARDHQKLER61EARICRLLKH71SNIVRLHDSI81SEEGFHYLVF91DLVTGGELFE
101-150101DIVAREYYSE111ADASHCIQQI121LEAVLHCHQM131GVVHRDLKPE141NLLLASKCKG
151-200151AAVKLADFGL161AIEVQGDQQA171WFGFAGTPGY181LSPEVLRKEA191YGKPVDIWAC
201-250201GVILYILLVG211YPPFWDEDQH221KLYQQIKAGA231YDFPSPEWDT241VTPEAKNLIN
251-300251QMLTINPAKR261ITAHEALKHP271WVCQRSTVAS281MMHRQETVEC291LKKFNARRKL
301-350301KGAILTTMLA311TRNFSARKQE321IIKTTEQLIE331AVNNGDFEAY341AKICDPGLTS
351-400351FEPEALGNLV361EGMDFHRFYF371ENLLAKNSKP381IHTTILNPHV391HVIGEDAACI
401-449401AYIRLTQYID411GQGRPRTSQS421EETRVWHRRD431GKWQNVHFHC441SGAPVAPLQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.02
|
|
| 31 | Protein kinase domain Protein kinase-like domain superfamily Phosphorylase Kinase Protein kinase, ATP binding site | - | - |
Deep-Palm: 0.62
|
|
| 35 | Protein kinase domain Protein kinase-like domain superfamily Phosphorylase Kinase | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.69
|
|
| 65 | - | - | - |
Deep-Palm: 0.86
|
|
| 116 | - | - | - |
Deep-Palm: 0.08
|
|
| 127 | - | - | - |
Deep-Palm: 0.13
|
|
| 148 | - | - | - |
Deep-Palm: 0.97
|
|
| 200 | - | - | - |
Deep-Palm: 0.82
|
|
| 273 | - | - | - |
Deep-Palm: 0.58
|
|
| 290 | - | - | - |
Deep-Palm: 0.97
|
|
| 434 | - | - | - |
Deep-Palm: 0.97
|
|
| 477 | - | - | - |
Deep-Palm: 0.97
|
|
| 520 | - | - | - |
Deep-Palm: 0.88
|
|
| 561 | - | - | - |
Deep-Palm: 0.85
|
|
| 616 | - | - | - |
Deep-Palm: 0.51
|
|
| 657 | - | - | - |
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
1
heart
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 30 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 66 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 66 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 66 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 75 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 114 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 260 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 273 | C → C | 0.001887 | SNP | Splice Region | UCEC |
| 633 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |