Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q13885 | TUBB2A; TUBB2 | Tubulin beta-2A chain (Tubulin beta … | Homo sapiens (Human) | 445 aa |
Protein Details: Q13885 (TUBB2A)
Protein Information
| Accession | Q13885 |
|---|---|
| Protein Names | Tubulin beta-2A chain (Tubulin beta class IIa) |
| Gene Symbol | TUBB2A; TUBB2 |
| Organism | Homo sapiens (Human) |
| Length | 445 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 36430497 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.720
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.720
36/46 (78.3%)
6
HAP1 cells
Specificity: 0.120
6/10 (60.0%)
4
293T cells
Specificity: 0.080
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.080
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHIQAG11QCGNQIGAKF21WEVISDEHGI31DPTGSYHGDS41DLQLERINVY
51-10051YNEAAGNKYV61PRAILVDLEP71GTMDSVRSGP81FGQIFRPDNF91VFGQSGAGNN
101-150101WAKGHYTEGA111ELVDSVLDVV121RKESESCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEYP161DRIMNTFSVM171PSPKVSDTVV181EPYNATLSVH191QLVENTDETY
201-250201SIDNEALYDI211CFRTLKLTTP221TYGDLNHLVS231ATMSGVTTCL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVPELT291QQMFDSKNMM
301-350301AACDPRHGRY311LTVAAIFRGR321MSMKEVDEQM331LNVQNKNSSY341FVEWIPNNVK
351-400351TAVCDIPPRG361LKMSATFIGN371STAIQELFKR381ISEQFTAMFR391RKAFLHWYTG
401-445401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431DEQGEFEEEE441GEDEA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 211 | Prediction (Medium) | - | - |
| 239 | Prediction (High) | - | - |
| 303 | Prediction (High) | - | - |
| 354 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Tubulin C-terminal domain | 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 213 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 391 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |