Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q14699 | RFTN1; KIAA0084; MIG2 | Raftlin (Cell migration-inducing gene 2 … | Homo sapiens (Human) | 578 aa |
Protein Details: Q14699 (RFTN1)
Protein Information
| Accession | Q14699 |
|---|---|
| Protein Names | Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) |
| Gene Symbol | RFTN1; KIAA0084; MIG2 |
| Organism | Homo sapiens (Human) |
| Length | 578 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 26111759 32944167 33636221 36430497 |
| Database Sources | dbPTM |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.389
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
7
Jurkat T cells
Specificity: 0.389
7/25 (28.0%)
4
T cells
Specificity: 0.222
4/4 (100.0%)
3
PC3 cells
Specificity: 0.167
3/4 (75.0%)
3
Cerebral cortex
Specificity: 0.167
3/4 (75.0%)
1
Liver membrane
Specificity: 0.056
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGCGLNKLEK11RDEKRPGNIY21STLKRPQVET31KIDVSYEYRF41LEFTTLSAAE
51-10051LPGSSAVRLA61SLRDLPAQLL71ELYQQGFSLA81ALHPFVQPTH91EREKTPLEHI
101-150101FRAILIKKTD111RSQKTDLHNE121GYILELDCCS131SLDHPTDQKL141IPEFIKKIQE
151-200151AASQGLKFVG161VIPQYHSSVN171SAGSSAPVST181ANSTEDARDA191KNARGDHASL
201-250201ENEKPGTGDV211CSAPAGRNQS221PEPSSGPRGE231VPLAKQPSSP241SGEGDGGELS
251-300251PQGVSKTLDG261PESNPLEVHE271EPLSGKMEIF281TLFNKPKSHQ291KCRQYYPVTI
301-350301PLHVSKNGQT311VSGLDANWLE321HMSDHFRKGG331MLVNAVFYLG341IVNDSLHGLT
351-400351DGVFIFEAVS361TEDSKTIQGY371DAIVVEQWTV381LEGVEVQTDY391VPLLNSLAAY
401-450401GWQLTCVLPT411PVVKTTSEGS421VSTKQIVFLQ431RPCLPQKIKK441KESKFQWRFS
451-500451REEMHNRQMR461KSKGKLSARD471KQQAEENEKN481LEDQSSKAGD491MGNCVSGQQQ
501-550501EGGVSEEMKG511PVQEDKGEQL521SPGGLLCGVG531VEGEAVQNGP541ASHSRALVGI
551-578551CTGHSNPGED561ARDGDAEEVR571ELGTVEEN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 3 | DBPTM Prediction (High) | Raftlin | - |
| 406 | Prediction (Medium) | - | - |
| 433 | Prediction (High) | - | - |
| 494 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 128 | C → C | 0.005618 | SNP | Silent | PAAD |
| 194 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 296 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |