Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q14767 | LTBP2 | Latent-transforming growth factor beta-binding protein … | Homo sapiens (Human) | 1821 aa |
Protein Details: Q14767 (LTBP2)
Protein Information
| Accession | Q14767 |
|---|---|
| Protein Names | Latent-transforming growth factor beta-binding protein 2 (LTBP-2) |
| Gene Symbol | LTBP2 |
| Organism | Homo sapiens (Human) |
| Length | 1821 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRPRTKARSP11GRALRNPWRG21FLPLTLALFV31GAGHAQRDPV41GRYEPAGGDA
51-10051NRLRRPGGSY61PAAAAAKVYS71LFREQDAPVA81GLQPVERAQP91GWGSPRRPTE
101-150101AEARRPSRAQ111QSRRVQPPAQ121TRRSTPLGQQ131QPAPRTRAAP141ALPRLGTPQR
151-200151SGAAPPTPPR161GRLTGRNVCG171GQCCPGWTTA181NSTNHCIKPV191CEPPCQNRGS
201-250201CSRPQLCVCR211SGFRGARCEE221VIPDEEFDPQ231NSRLAPRRWA241ERSPNLRRSS
251-300251AAGEGTLARA261QPPAPQSPPA271PQSPPAGTLS281GLSQTHPSQQ291HVGLSRTVRL
301-350301HPTATASSQL311SSNALPPGPG321LEQRDGTQQA331VPLEHPSSPW341GLNLTEKIKK
351-400351IKIVFTPTIC361KQTCARGHCA371NSCERGDTTT381LYSQGGHGHD391PKSGFRIYFC
401-450401QIPCLNGGRC411IGRDECWCPA421NSTGKFCHLP431IPQPDREPPG441RGSRPRALLE
451-500451APLKQSTFTL461PLSNQLASVN471PSLVKVHIHH481PPEASVQIHQ491VAQVRGGVEE
501-550501ALVENSVETR511PPPWLPASPG521HSLWDSNNIP531ARSGEPPRPL541PPAAPRPRGL
551-600551LGRCYLNTVN561GQCANPLLEL571TTQEDCCGSV581GAFWGVTLCA591PCPPRPASPV
601-650601IENGQLECPQ611GYKRLNLTHC621QDINECLTLG631LCKDAECVNT641RGSYLCTCRP
651-700651GLMLDPSRSR661CVSDKAISML671QGLCYRSLGP681GTCTLPLAQR691ITKQICCCSR
701-750701VGKAWGSECE711KCPLPGTEAF721REICPAGHGY731TYASSDIRLS741MRKAEEEELA
751-800751RPPREQGQRS761SGALPGPAER771QPLRVVTDTW781LEAGTIPDKG791DSQAGQVTTS
801-850801VTHAPAWVTG811NATTPPMPEQ821GIAEIQEEQV831TPSTDVLVTL841STPGIDRCAA
851-900851GATNVCGPGT861CVNLPDGYRC871VCSPGYQLHP881SQAYCTDDNE891CLRDPCKGKG
901-950901RCINRVGSYS911CFCYPGYTLA921TSGATQECQD931INECEQPGVC941SGGQCTNTEG
951-1000951SYHCECDQGY961IMVRKGHCQD971INECRHPGTC981PDGRCVNSPG991SYTCLACEEG
1001-10501001YRGQSGSCVD1011VNECLTPGVC1021AHGKCTNLEG1031SFRCSCEQGY1041EVTSDEKGCQ
1051-11001051DVDECASRAS1061CPTGLCLNTE1071GSFACSACEN1081GYWVNEDGTA1091CEDLDECAFP
1101-11501101GVCPSGVCTN1111TAGSFSCKDC1121DGGYRPSPLG1131DSCEDVDECE1141DPQSSCLGGE
1151-12001151CKNTVGSYQC1161LCPQGFQLAN1171GTVCEDVNEC1181MGEEHCAPHG1191ECLNSHGSFF
1201-12501201CLCAPGFVSA1211EGGTSCQDVD1221ECATTDPCVG1231GHCVNTEGSF1241NCLCETGFQP
1251-13001251SPESGECVDI1261DECEDYGDPV1271CGTWKCENSP1281GSYRCVLGCQ1291PGFHMAPNGD
1301-13501301CIDIDECAND1311TMCGSHGFCD1321NTDGSFRCLC1331DQGFEISPSG1341WDCVDVNECE
1351-14001351LMLAVCGAAL1361CENVEGSFLC1371LCASDLEEYD1381AQEGHCRPRG1391AGGQSMSEAP
1401-14501401TGDHAPAPTR1411MDCYSGQKGH1421APCSSVLGRN1431TTQAECCCTQ1441GASWGDACDL
1451-15001451CPSEDSAEFS1461EICPSGKGYI1471PVEGAWTFGQ1481TMYTDADECV1491IFGPGLCPNG
1501-15501501RCLNTVPGYV1511CLCNPGFHYD1521ASHKKCEDHD1531ECQDLACENG1541ECVNTEGSFH
1551-16001551CFCSPPLTLD1561LSQQRCMNST1571SSTEDLPDHD1581IHMDICWKKV1591TNDVCSEPLR
1601-16501601GHRTTYTECC1611CQDGEAWSQQ1621CALCPPRSSE1631VYAQLCNVAR1641IEAEREAGVH
1651-17001651FRPGYEYGPG1661PDDLHYSIYG1671PDGAPFYNYL1681GPEDTVPEPA1691FPNTAGHSAD
1701-17501701RTPILESPLQ1711PSELQPHYVA1721SHPEPPAGFE1731GLQAEECGIL1741NGCENGRCVR
1751-18001751VREGYTCDCF1761EGFQLDAAHM1771ACVDVNECDD1781LNGPAVLCVH1791GYCENTEGSY
1801-18211801RCHCSPGYVA1811EAGPPHCTAK1821E
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 169 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.28
|
|
| 173 | - | - | - |
Deep-Palm: 0.07
|
|
| 174 | - | - | - |
Deep-Palm: 0.06
|
|
| 186 | - | - | - |
Deep-Palm: 0.02
|
|
| 191 | - | - | - |
Deep-Palm: 0.03
|
|
| 195 | - | - | - |
Deep-Palm: 0.02
|
|
| 201 | - | - | - |
Deep-Palm: 0.08
|
|
| 207 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.17
|
|
| 209 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.12
|
|
| 218 | - | - | - |
Deep-Palm: 0.18
|
|
| 360 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.27
|
|
| 364 | - | - | - |
Deep-Palm: 0.09
|
|
| 369 | - | - | - |
Deep-Palm: 0.08
|
|
| 373 | - | - | - |
Deep-Palm: 0.09
|
|
| 400 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.15
|
|
| 404 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.02
|
|
| 410 | - | - | - |
Deep-Palm: 0.01
|
|
| 416 | - | - | - |
Deep-Palm: 0.02
|
|
| 418 | - | - | - |
Deep-Palm: 0.02
|
|
| 427 | - | - | - |
Deep-Palm: 0.10
|
|
| 554 | - | - | - |
Deep-Palm: 0.98
|
|
| 563 | - | - | - |
Deep-Palm: 0.33
|
|
| 576 | - | - | - |
Deep-Palm: 0.34
|
|
| 577 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.19
|
|
| 589 | - | - | - |
Deep-Palm: 0.39
|
|
| 592 | - | - | - |
Deep-Palm: 0.69
|
|
| 608 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.34
|
|
| 620 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.28
|
|
| 626 | - | - | - |
Deep-Palm: 0.11
|
|
| 632 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.04
|
|
| 637 | - | - | - |
Deep-Palm: 0.10
|
|
| 646 | - | - | - |
Deep-Palm: 0.36
|
|
| 648 | - | - | - |
Deep-Palm: 0.45
|
|
| 661 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.59
|
|
| 674 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.94
|
|
| 683 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.85
|
|
| 696 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.95
Deep-Palm: 0.82
|
|
| 697 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.95
Deep-Palm: 0.68
|
|
| 698 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.95
Deep-Palm: 0.61
|
|
| 709 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.37
|
|
| 712 | - | - | - |
Deep-Palm: 0.84
|
|
| 724 | - | - | - |
Deep-Palm: 0.60
|
|
| 848 | - | - | - |
Deep-Palm: 0.65
|
|
| 856 | - | - | - |
Deep-Palm: 0.17
|
|
| 861 | - | - | - |
Deep-Palm: 0.07
|
|
| 870 | - | - | - |
Deep-Palm: 0.03
|
|
| 872 | - | - | - |
Deep-Palm: 0.05
|
|
| 885 | - | - | - |
Deep-Palm: 0.02
|
|
| 891 | - | - | - |
Deep-Palm: 0.02
|
|
| 896 | - | - | - |
Deep-Palm: 0.02
|
|
| 902 | - | - | - |
Deep-Palm: 0.02
|
|
| 911 | - | - | - |
Deep-Palm: 0.16
|
|
| 913 | - | - | - |
Deep-Palm: 0.19
|
|
| 928 | - | - | - |
Deep-Palm: 0.05
|
|
| 934 | - | - | - |
Deep-Palm: 0.03
|
|
| 940 | - | - | - |
Deep-Palm: 0.02
|
|
| 945 | - | - | - |
Deep-Palm: 0.02
|
|
| 954 | - | - | - |
Deep-Palm: 0.02
|
|
| 956 | - | - | - |
Deep-Palm: 0.02
|
|
| 968 | - | - | - |
Deep-Palm: 0.02
|
|
| 974 | - | - | - |
Deep-Palm: 0.02
|
|
| 980 | - | - | - |
Deep-Palm: 0.02
|
|
| 985 | - | - | - |
Deep-Palm: 0.02
|
|
| 994 | - | - | - |
Deep-Palm: 0.12
|
|
| 997 | - | - | - |
Deep-Palm: 0.11
|
|
| 1008 | - | - | - |
Deep-Palm: 0.11
|
|
| 1014 | - | - | - |
Deep-Palm: 0.10
|
|
| 1020 | - | - | - |
Deep-Palm: 0.06
|
|
| 1025 | - | - | - |
Deep-Palm: 0.03
|
|
| 1034 | - | - | - |
Deep-Palm: 0.05
|
|
| 1036 | - | - | - |
Deep-Palm: 0.07
|
|
| 1049 | - | - | - |
Deep-Palm: 0.04
|
|
| 1055 | - | - | - |
Deep-Palm: 0.11
|
|
| 1061 | - | - | - |
Deep-Palm: 0.21
|
|
| 1066 | - | - | - |
Deep-Palm: 0.24
|
|
| 1075 | - | - | - |
Deep-Palm: 0.12
|
|
| 1078 | - | - | - |
Deep-Palm: 0.09
|
|
| 1091 | - | - | - |
Deep-Palm: 0.04
|
|
| 1097 | - | - | - |
Deep-Palm: 0.05
|
|
| 1103 | - | - | - |
Deep-Palm: 0.14
|
|
| 1108 | - | - | - |
Deep-Palm: 0.06
|
|
| 1117 | - | - | - |
Deep-Palm: 0.11
|
|
| 1120 | - | - | - |
Deep-Palm: 0.10
|
|
| 1133 | - | - | - |
Deep-Palm: 0.06
|
|
| 1139 | - | - | - |
Deep-Palm: 0.04
|
|
| 1146 | - | - | - |
Deep-Palm: 0.04
|
|
| 1151 | - | - | - |
Deep-Palm: 0.05
|
|
| 1160 | - | - | - |
Deep-Palm: 0.28
|
|
| 1162 | - | - | - |
Deep-Palm: 0.38
|
|
| 1174 | - | - | - |
Deep-Palm: 0.02
|
|
| 1180 | - | - | - |
Deep-Palm: 0.02
|
|
| 1186 | - | - | - |
Deep-Palm: 0.01
|
|
| 1192 | - | - | - |
Deep-Palm: 0.02
|
|
| 1201 | - | - | - |
Deep-Palm: 0.07
|
|
| 1203 | - | - | - |
Deep-Palm: 0.06
|
|
| 1216 | - | - | - |
Deep-Palm: 0.07
|
|
| 1222 | - | - | - |
Deep-Palm: 0.02
|
|
| 1228 | - | - | - |
Deep-Palm: 0.02
|
|
| 1233 | - | - | - |
Deep-Palm: 0.02
|
|
| 1242 | - | - | - |
Deep-Palm: 0.03
|
|
| 1244 | - | - | - |
Deep-Palm: 0.04
|
|
| 1257 | - | - | - |
Deep-Palm: 0.02
|
|
| 1263 | - | - | - |
Deep-Palm: 0.02
|
|
| 1271 | - | - | - |
Deep-Palm: 0.02
|
|
| 1276 | - | - | - |
Deep-Palm: 0.03
|
|
| 1285 | - | - | - |
Deep-Palm: 0.03
|
|
| 1289 | - | - | - |
Deep-Palm: 0.03
|
|
| 1301 | - | - | - |
Deep-Palm: 0.01
|
|
| 1307 | - | - | - |
Deep-Palm: 0.01
|
|
| 1313 | - | - | - |
Deep-Palm: 0.01
|
|
| 1319 | - | - | - |
Deep-Palm: 0.01
|
|
| 1328 | - | - | - |
Deep-Palm: 0.03
|
|
| 1330 | - | - | - |
Deep-Palm: 0.03
|
|
| 1343 | - | - | - |
Deep-Palm: 0.03
|
|
| 1349 | - | - | - |
Deep-Palm: 0.18
|
|
| 1356 | - | - | - |
Deep-Palm: 0.05
|
|
| 1361 | - | - | - |
Deep-Palm: 0.15
|
|
| 1370 | - | - | - |
Deep-Palm: 0.43
|
|
| 1372 | - | - | - |
Deep-Palm: 0.34
|
|
| 1386 | - | - | - |
Deep-Palm: 0.73
|
|
| 1413 | - | - | - |
Deep-Palm: 0.56
|
|
| 1423 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.17
|
|
| 1436 | - | - | - |
Deep-Palm: 0.24
|
|
| 1437 | - | - | - |
Deep-Palm: 0.22
|
|
| 1438 | - | - | - |
Deep-Palm: 0.22
|
|
| 1448 | - | - | - |
Deep-Palm: 0.15
|
|
| 1451 | - | - | - |
Deep-Palm: 0.20
|
|
| 1463 | - | - | - |
Deep-Palm: 0.57
|
|
| 1489 | - | - | - |
Deep-Palm: 0.06
|
|
| 1497 | - | - | - |
Deep-Palm: 0.05
|
|
| 1502 | - | - | - |
Deep-Palm: 0.05
|
|
| 1511 | - | - | - |
Deep-Palm: 0.05
|
|
| 1513 | - | - | - |
Deep-Palm: 0.07
|
|
| 1526 | - | - | - |
Deep-Palm: 0.02
|
|
| 1532 | - | - | - |
Deep-Palm: 0.02
|
|
| 1537 | - | - | - |
Deep-Palm: 0.02
|
|
| 1542 | - | - | - |
Deep-Palm: 0.01
|
|
| 1551 | - | - | - |
Deep-Palm: 0.06
|
|
| 1553 | - | - | - |
Deep-Palm: 0.06
|
|
| 1566 | - | - | - |
Deep-Palm: 0.20
|
|
| 1586 | - | - | - |
Deep-Palm: 0.07
|
|
| 1595 | SWISSPALM DBPTM CYSMODDB | TB domain | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.05
|
| 1609 | - | - | - |
Deep-Palm: 0.05
|
|
| 1610 | - | - | - |
Deep-Palm: 0.05
|
|
| 1611 | - | - | - |
Deep-Palm: 0.05
|
|
| 1621 | - | - | - |
Deep-Palm: 0.06
|
|
| 1624 | - | - | - |
Deep-Palm: 0.09
|
|
| 1636 | - | - | - |
Deep-Palm: 0.87
|
|
| 1737 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.52
|
|
| 1743 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.21
|
|
| 1748 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.03
|
|
| 1757 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.04
|
|
| 1759 | - | - | - |
Deep-Palm: 0.06
|
|
| 1772 | - | - | - |
Deep-Palm: 0.03
|
|
| 1778 | - | - | - |
Deep-Palm: 0.05
|
|
| 1788 | - | - | - |
Deep-Palm: 0.02
|
|
| 1793 | - | - | - |
Deep-Palm: 0.02
|
|
| 1802 | - | - | - |
Deep-Palm: 0.02
|
|
| 1804 | - | - | - |
Deep-Palm: 0.03
|
|
| 1817 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 217 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 218 | C → C | 0.001887 | SNP | Silent | UCEC |
| 369 | C → R | 0.002288 | SNP | Missense Mutation | STAD |
| 578 | G → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 632 | C → R | 0.001969 | SNP | Missense Mutation | HNSC |
| 648 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 738 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 873 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 901 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 928 | C → C | 0.002506 | SNP | Silent | COAD |
| 954 | C → C | 0.001887 | SNP | Silent | UCEC |
| 985 | C → C | 0.002288 | SNP | Silent | STAD |
| 985 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 985 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 1014 | C → Ffs*2 | 0.003559 | DEL | Frame Shift Del | KIRP |
| 1014 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 1055 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 1097 | C → C | 0.001887 | SNP | Silent | UCEC |
| 1200 | F → C | 0.002294 | SNP | Missense Mutation | OV |
| 1222 | C → R | 0.001014 | SNP | Missense Mutation | BRCA |
| 1307 | C → C | 0.002506 | SNP | Silent | COAD |
| 1502 | C → R | 0.002506 | SNP | Missense Mutation | COAD |
| 1553 | C → C | 0.003559 | SNP | Silent | KIRP |
| 1565 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 1600 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1600 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1611 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 1636 | C → F | 0.002141 | SNP | Missense Mutation | SKCM |
| 1640 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1737 | C → C | 0.002506 | SNP | Silent | COAD |
| 1737 | C → C | 0.001887 | SNP | Silent | UCEC |
| 1772 | C → C | 0.001969 | SNP | Silent | HNSC |
| 1788 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 637* | C → ? | 0.001764 | SNP | Nonsense Mutation | LUAD |
| 848* | C → ? | 0.001764 | INS | Nonsense Mutation | LUAD |
| 1257* | C → ? | 0.002033 | SNP | Nonsense Mutation | LUSC |