Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q15008 | PSMD6 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 389 aa |
Protein Details: Q15008 (PSMD6)
Protein Information
| Accession | Q15008 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A) |
| Gene Symbol | PSMD6 |
| Organism | Homo sapiens (Human) |
| Length | 389 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPLENLEEEG11LPKNPDLRIA21QLRFLLSLPE31HRGDAAVRDE41LMAAVRDNNM
51-10051APYYEALCKS61LDWQIDVDLL71NKMKKANEDE81LKRLDEELED91AEKNLGESEI
101-150101RDAMMAKAEY111LCRIGDKEGA121LTAFRKTYDK131TVALGHRLDI141VFYLLRIGLF
151-200151YMDNDLITRN161TEKAKSLIEE171GGDWDRRNRL181KVYQGLYCVA191IRDFKQAAEL
201-250201FLDTVSTFTS211YELMDYKTFV221TYTVYVSMIA231LERPDLREKV241IKGAEILEVL
251-300251HSLPAVRQYL261FSLYECRYSV271FFQSLAVVEQ281EMKKDWLFAP291HYRYYVREMR
301-350301IHAYSQLLES311YRSLTLGYMA321EAFGVGVEFI331DQELSRFIAA341GRLHCKIDKV
351-389351NEIVETNRPD361SKNWQYQETI371KKGDLLLNRV381QKLSRVINM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 58 | - | - | - |
Deep-Palm: 0.50
|
|
| 112 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.94
|
|
| 188 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.94
|
|
| 266 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.76
|
|
| 345 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
HAP1 cell
Specificity: 0.667
2/2 (100.0%)
1
293T cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 32 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 101 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 179 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 185 | G → C | 0.002288 | SNP | Missense Mutation | STAD |
| 192 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 267 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |