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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q15012 LAPTM4A Lysosomal-associated transmembrane protein 4A (Golgi … Homo sapiens (Human) 233 aa

Protein Details: Q15012 (LAPTM4A)

Protein Information
AccessionQ15012
Protein NamesLysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane-spanning transporter MTP)
Gene SymbolLAPTM4A
OrganismHomo sapiens (Human)
Length233 aa
IsoformsNo isoforms
Related PMIDs 24357059 29733200 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVSMSFKRNR11SDRFYSTRCC21GCCHVRTGTI31ILGTWYMVVN41LLMAILLTVE
51-10051VTHPNSMPAV61NIQYEVIGNY71YSSERMADNA81CVLFAVSVLM91FIISSMLVYG
101-150101AISYQVGWLI111PFFCYRLFDF121VLSCLVAISS131LTYLPRIKEY141LDQLPDFPYK
151-200151DDLLALDSSC161LLFIVLVFFA171LFIIFKAYLI181NCVWNCYKYI191NNRNVPEIAV
201-233201YPAFEAPPQY211VLPTYEMAVK221MPEKEPPPPY231LPA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
19 SWISSPALM DBPTM CYSMODDB Lysosomal-associated transmembrane transporter - -
Deep-Palm: 0.75
20 SWISSPALM DBPTM CYSMODDB Lysosomal-associated transmembrane transporter - -
GPS-Palm: 0.88
Deep-Palm: 0.71
22 SWISSPALM DBPTM CYSMODDB Lysosomal-associated transmembrane transporter - -
GPS-Palm: 0.76
Deep-Palm: 0.52
23 SWISSPALM DBPTM CYSMODDB Lysosomal-associated transmembrane transporter - -
GPS-Palm: 0.86
Deep-Palm: 0.51
81 - - -
Deep-Palm: 0.13
114 - - -
GPS-Palm: 0.82
Deep-Palm: 0.62
124 - - -
GPS-Palm: 0.74
Deep-Palm: 0.87
160 - - -
Deep-Palm: 0.59
182 - - -
GPS-Palm: 0.77
Deep-Palm: 0.03
186 - - -
Deep-Palm: 0.05
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
PC3
Specificity: 0.600
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.200
1/1 (100.0%)
1
HUVECs
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine