Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q15365 | PCBP1 | Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous … | Homo sapiens (Human) | 356 aa |
Protein Details: Q15365 (PCBP1)
Protein Information
| Accession | Q15365 |
|---|---|
| Protein Names | Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3) |
| Gene Symbol | PCBP1 |
| Organism | Homo sapiens (Human) |
| Length | 356 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 29575903 29733200 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.510
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 0.510
26/46 (56.5%)
10
HAP1 cells
Specificity: 0.196
10/10 (100.0%)
4
PC3 cells
Specificity: 0.078
4/4 (100.0%)
4
293T cells
Specificity: 0.078
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.078
4/4 (100.0%)
2
Jurkat T cells
Specificity: 0.039
2/25 (8.0%)
1
U937 cells
Specificity: 0.020
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDAGVTESGL11NVTLTIRLLM21HGKEVGSIIG31KKGESVKRIR41EESGARINIS
51-10051EGNCPERIIT61LTGPTNAIFK71AFAMIIDKLE81EDINSSMTNS91TAASRPPVTL
101-150101RLVVPATQCG111SLIGKGGCKI121KEIRESTGAQ131VQVAGDMLPN141STERAITIAG
151-200151VPQSVTECVK161QICLVMLETL171SQSPQGRVMT181IPYQPMPASS191PVICAGGQDR
201-250201CSDAAGYPHA211THDLEGPPLD221AYSIQGQHTI231SPLDLAKLNQ241VARQQSHFAM
251-300251MHGGTGFAGI261DSSSPEVKGY271WASLDASTQT281THELTIPNNL291IGCIIGRQGA
301-350301NINEIRQMSG311AQIKIANPVE321GSSGRQVTIT331GSAASISLAQ341YLINARLSSE
351-356351KGMGCS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 54 | CYSMODDB SWISSPALM DBPTM | KH domain | - |
| 109 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | KH domain | 29575903 |
| 118 | Prediction (Low) | - | - |
| 158 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 163 | Prediction (Low) | - | - |
| 194 | Experimental | - | 19801377 |
| 293 | Prediction (Medium) | - | - |
| 355 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 54 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 355 | C → Vfs*11 | 0.002288 | INS | Frame Shift Ins | STAD |