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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q16585 SGCB Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated … Homo sapiens (Human) 318 aa

Protein Details: Q16585 (SGCB)

Protein Information
AccessionQ16585
Protein NamesBeta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b)
Gene SymbolSGCB
OrganismHomo sapiens (Human)
Length318 aa
IsoformsNo isoforms
Related PMIDs 33636221
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAAAAAAAE11QQSSNGPVKK21SMREKAVERR31SVNKEHNSNF41KAGYIPIDED
51-10051RLHKTGLRGR61KGNLAICVII71LLFILAVINL81IITLVIWAVI91RIGPNGCDSM
101-150101EFHESGLLRF111KQVSDMGVIH121PLYKSTVGGR131RNENLVITGN141NQPIVFQQGT
151-200151TKLSVENNKT161SITSDIGMQF171FDPRTQNILF181STDYETHEFH191LPSGVKSLNV
201-250201QKASTERITS211NATSDLNIKV221DGRAIVRGNE231GVFIMGKTIE241FHMGGNMELK
251-300251AENSIILNGS261VMVSTTRLPS271SSSGDQLGSG281DWVRYKLCMC291ADGTLFKVQV
301-318301TSQNMGCQIS311DNPCGNTH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
67 - - -
GPS-Palm: 0.87
Deep-Palm: 0.95
97 - - -
GPS-Palm: 0.72
Deep-Palm: 0.70
288 - - -
GPS-Palm: 0.86
Deep-Palm: 0.73
290 - - -
GPS-Palm: 0.83
Deep-Palm: 0.48
307 - - -
Deep-Palm: 0.01
314 - - -
GPS-Palm: 0.89
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
67 C → F 0.007299 SNP Missense Mutation READ
223 R → C 0.002288 SNP Missense Mutation STAD
223 R → C 0.002506 SNP Missense Mutation COAD