Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q16586-2 | SGCA | Alpha-sarcoglycan (Alpha-SG) (50 kDa dystrophin-associated … | Homo sapiens (Human) | 263 aa |
Protein Details: Q16586-2 (SGCA)
Protein Information
| Accession | Q16586-2 |
|---|---|
| Protein Names | Alpha-sarcoglycan (Alpha-SG) (50 kDa dystrophin-associated glycoprotein) (50DAG) (Adhalin) (Dystroglycan-2) |
| Gene Symbol | SGCA |
| Organism | Homo sapiens (Human) |
| Length | 263 aa |
| Isoforms | |
| Related PMIDs | 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAETLFWTPL11LVVLLAGLGD21TEAQQTTLHP31LVGRVFVHTL41DHETFLSLPE
51-10051HVAVPPAVHI61TYHAHLQGHP71DLPRWLRYTQ81RSPHHPGFLY91GSATPEDRGL
101-150101QVIEVTAYNR111DSFDTTRQRL121VLEIGDPEGP131LLPYQAEFLV141RSHDAEEVLP
151-200151STPASRFLSA161LGGLWEPGEL171QLLNVTSALD181RGGRVPLPIE191GRKEGLKRDL
201-250201ATSDIQMVHH211CTIHGNTEEL221RQMAASREVP231RPLSTLPMFN241VHTGERLPPR
251-263251VDSAQVPLIL261DQH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 209 | - | - | - |
Deep-Palm: 0.74
|
|
| 222 | - | - | - |
Deep-Palm: 0.65
|
|
| 232 | - | - | - |
Deep-Palm: 0.36
|
|
| 245 | - | - | - |
Deep-Palm: 0.34
|
|
| 276 | - | - | - |
Deep-Palm: 0.78
|
|
| 313 | - | - | - |
Deep-Palm: 0.98
|
|
| 314 | - | - | - |
Deep-Palm: 0.98
|
|
| 335 | - | - | - |
Deep-Palm: 0.33
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 141 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 207 | S → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 215 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 265 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 335 | C → C | 0.002506 | SNP | Silent | COAD |
| 368 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |