Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q16658 | FSCN1; FAN1; HSN; SNL | Fascin (55 kDa actin-bundling protein) … | Homo sapiens (Human) | 493 aa |
Protein Details: Q16658 (FSCN1)
Protein Information
| Accession | Q16658 |
|---|---|
| Protein Names | Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) |
| Gene Symbol | FSCN1; FAN1; HSN; SNL |
| Organism | Homo sapiens (Human) |
| Length | 493 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 29575903 29733200 32944167 36430497 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.417
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
10
HAP1 cells
Specificity: 0.417
10/10 (100.0%)
4
PC3 cells
Specificity: 0.167
4/4 (100.0%)
4
293T cells
Specificity: 0.167
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.167
4/4 (100.0%)
1
HeLa cells
Specificity: 0.042
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.042
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTANGTAEAV11QIQFGLINCG21NKYLTAEAFG31FKVNASASSL41KKKQIWTLEQ
51-10051PPDEAGSAAV61CLRSHLGRYL71AADKDGNVTC81EREVPGPDCR91FLIVAHDDGR
101-150101WSLQSEAHRR111YFGGTEDRLS121CFAQTVSPAE131KWSVHIAMHP141QVNIYSVTRK
151-200151RYAHLSARPA161DEIAVDRDVP171WGVDSLITLA181FQDQRYSVQT191ADHRFLRHDG
201-250201RLVARPEPAT211GYTLEFRSGK221VAFRDCEGRY231LAPSGPSGTL241KAGKATKVGK
251-300251DELFALEQSC261AQVVLQAANE271RNVSTRQGMD281LSANQDEETD291QETFQLEIDR
301-350301DTKKCAFRTH311TGKYWTLTAT321GGVQSTASSK331NASCYFDIEW341RDRRITLRAS
351-400351NGKFVTSKKN361GQLAASVETA371GDSELFLMKL381INRPIIVFRG391EHGFIGCRKV
401-450401TGTLDANRSS411YDVFQLEFND421GAYNIKDSTG431KYWTVGSDSA441VTSSGDTPVD
451-493451FFFEFCDYNK461VAIKVGGRYL471KGDHAGVLKA481SAETVDPASL491WEY
Palmitoylation Sites Details
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 47 | C → R | 0.002545 | SNP | Missense Mutation | GBM |
| 68 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 100 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 220 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 300 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 308 | V → Cfs*5 | 0.001014 | DEL | Frame Shift Del | BRCA |
| 383 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 398 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 456 | C → C | 0.001014 | SNP | Silent | BRCA |
| 468 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 468 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 469 | Y → C | 0.002545 | SNP | Missense Mutation | GBM |
| 743 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 812 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 824 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 833 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 944 | C → C | 0.002506 | SNP | Silent | COAD |
| 954 | C → C | 0.001887 | SNP | Silent | UCEC |
| 1004 | C → C | 0.002545 | SNP | Silent | GBM |