Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q16698-2 DECR1 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC … Homo sapiens (Human) 326 aa

Protein Details: Q16698-2 (DECR1)

Protein Information
AccessionQ16698-2
Protein Names2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)
Gene SymbolDECR1
OrganismHomo sapiens (Human)
Length326 aa
Isoforms
Related PMIDs 31251020 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGLGKKHLL11LMGEFFSYGT21KILYQNTEAL31QSKFFSPLQK41AMLPPNSFQG
51-10051KVAFITGGGT61GLGKGMTTLL71SSLGAQCVIA81SRKMDVLKAT91AEQISSQTGN
101-150101KVHAIQCDVR111DPDMVQNTVS121ELIKVAGHPN131IVINNAAGNF141ISPTERLSPN
151-200151AWKTITDIVL161NGTAFVTLEI171GKQLIKAQKG181AAFLSITTIY191AETGSGFVVP
201-250201SASAKAGVEA211MSKSLAAEWG221KYGMRFNVIQ231PGPIKTKGAF241SRLDPTGTFE
251-300251KEMIGRIPCG261RLGTVEELAN271LAAFLCSDYA281SWINGAVIKF291DGGEEVLISG
301-326301EFNDLRKVTK311EQWDTIEELI321RKTKGS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
17 - - -
Deep-Palm: 0.97
77 - - -
GPS-Palm: 0.92
86 - - -
Deep-Palm: 0.98
116 - - -
Deep-Palm: 0.52
259 - - -
GPS-Palm: 0.90
268 - - -
Deep-Palm: 0.98
285 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
86 C → C 0.001887 SNP Silent UCEC