Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q16719 | KYNU | Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) | Homo sapiens (Human) | 465 aa |
Protein Details: Q16719 (KYNU)
Protein Information
| Accession | Q16719 |
|---|---|
| Protein Names | Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) |
| Gene Symbol | KYNU |
| Organism | Homo sapiens (Human) |
| Length | 465 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEPSSLELPA11DTVQRIAAEL21KCHPTDERVA31LHLDEEDKLR41HFRECFYIPK
51-10051IQDLPPVDLS61LVNKDENAIY71FLGNSLGLQP81KMVKTYLEEE91LDKWAKIAAY
101-150101GHEVGKRPWI111TGDESIVGLM121KDIVGANEKE131IALMNALTVN141LHLLMLSFFK
151-200151PTPKRYKILL161EAKAFPSDHY171AIESQLQLHG181LNIEESMRMI191KPREGEETLR
201-250201IEDILEVIEK211EGDSIAVILF221SGVHFYTGQH231FNIPAITKAG241QAKGCYVGFD
251-300251LAHAVGNVEL261YLHDWGVDFA271CWCSYKYLNA281GAGGIAGAFI291HEKHAHTIKP
301-350301ALVGWFGHEL311STRFKMDNKL321QLIPGVCGFR331ISNPPILLVC341SLHASLEIFK
351-400351QATMKALRKK361SVLLTGYLEY371LIKHNYGKDK381AATKKPVVNI391ITPSHVEERG
401-450401CQLTITFSVP411NKDVFQELEK421RGVVCDKRNP431NGIRVAPVPL441YNSFHDVYKF
451-465451TNLLTSILDS461AETKN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 22 | Pyridoxal phosphate-dependent transferase, small domain | - | - |
Deep-Palm: 0.94
|
|
| 45 | Pyridoxal phosphate-dependent transferase, small domain | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.92
|
|
| 245 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.91
|
|
| 271 | - | - | - |
Deep-Palm: 0.64
|
|
| 273 | - | - | - |
Deep-Palm: 0.74
|
|
| 327 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.92
|
| 340 | - | - | - |
Deep-Palm: 0.90
|
|
| 401 | - | - | - |
Deep-Palm: 0.36
|
|
| 425 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | C → Y | 0.002545 | SNP | Missense Mutation | GBM |
| 45 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 109 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 271 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 273 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 376 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 401 | C → Afs*3 | 0.002288 | DEL | Frame Shift Del | STAD |