Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q1RMG2 | AHCY | Adenosylhomocysteinase (EC 3.13.2.1) | Homo sapiens (Human) | 306 aa |
Protein Details: Q1RMG2 (AHCY)
Protein Information
| Accession | Q1RMG2 |
|---|---|
| Protein Names | Adenosylhomocysteinase (EC 3.13.2.1) |
| Gene Symbol | AHCY |
| Organism | Homo sapiens (Human) |
| Length | 306 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 26876311 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MILDDGGDLT11NLIHTKYPQL21LPGIRGISEE31TTTGVHNLYK41MMANGILKVP
51-10051AINVNDSVTK61SKFDNLYGCR71ESLIDGIKRA81TDVMIAGKVA91VVAGYGDVGK
101-150101GCAQALRGFG111ARVIITEIDP121INALQAAMEG131YEVTTMDEAC141QEGNIFVTTT
151-200151GCIDIILGRH161FEQMKDDAIV171CNIGHFDVEI181DVKWLNENAV191EKVNIKPQVD
201-250201RYRLKNGRRI211ILLAEGRLVN221LGCAMGHPSF231VMSNSFTNQV241MAQIELWTHP
251-300251DKYPVGVHFL261PKKLDEAVAE271AHLGKLNVKL281TKLTEKQAQY291LGMSCDGPFK
301-306301PDHYRY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 69 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.76
|
|
| 102 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.98
|
|
| 140 | - | - | - |
Deep-Palm: 0.27
|
|
| 152 | - | - | - |
Deep-Palm: 0.55
|
|
| 171 | - | - | - |
Deep-Palm: 0.30
|
|
| 223 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.97
|
|
| 295 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.06
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.286
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
1
EC cell
Specificity: 0.071
1/1 (100.0%)
1
frontal cortex
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 421 | C → Y | 0.007299 | SNP | Missense Mutation | READ |