Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q29983 | MICA | MHC class I polypeptide-related sequence … | Homo sapiens (Human) | 383 aa |
Protein Details: Q29983 (MICA)
Protein Information
| Accession | Q29983 |
|---|---|
| Protein Names | MHC class I polypeptide-related sequence A (MIC-A) |
| Gene Symbol | MICA |
| Organism | Homo sapiens (Human) |
| Length | 383 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLGPVFLLL11AGIFPFAPPG21AAAEPHSLRY31NLTVLSWDGS41VQSGFLTEVH
51-10051LDGQPFLRCD61RQKCRAKPQG71QWAEDVLGNK81TWDRETRDLT91GNGKDLRMTL
101-150101AHIKDQKEGL111HSLQEIRVCE121IHEDNSTRSS131QHFYYDGELF141LSQNLETKEW
151-200151TMPQSSRAQT161LAMNVRNFLK171EDAMKTKTHY181HAMHADCLQE191LRRYLKSGVV
201-250201LRRTVPPMVN211VTRSEASEGN221ITVTCRASGF231YPWNITLSWR241QDGVSLSHDT
251-300251QQWGDVLPDG261NGTYQTWVAT271RICQGEEQRF281TCYMEHSGNH291STHPVPSGKV
301-350301LVLQSHWQTF311HVSAVAAAAI321FVIIIFYVRC331CKKKTSAAEG341PELVSLQVLD
351-383351QHPVGTSDHR361DATQLGFQPL371MSDLGSTGST381EGA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 59 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.84
|
|
| 64 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.74
|
|
| 119 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.35
|
|
| 187 | - | - | - |
Deep-Palm: 0.86
|
|
| 225 | - | - | - |
Deep-Palm: 0.36
|
|
| 273 | - | - | - |
Deep-Palm: 0.18
|
|
| 282 | - | - | - |
Deep-Palm: 0.04
|
|
| 330 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.95
|
| 331 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 29 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 134 | Y → C | 0.004219 | SNP | Missense Mutation | SARC |
| 213 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 329 | C → C | 0.001887 | SNP | Silent | UCEC |
| 282* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |