Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q2TBE6 | Pi4k2a | Phosphatidylinositol 4-kinase type 2-alpha (EC … | Mus musculus (Mouse) | 479 aa |
Protein Details: Q2TBE6 (Pi4k2a)
Protein Information
| Accession | Q2TBE6 |
|---|---|
| Protein Names | Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha) |
| Gene Symbol | Pi4k2a |
| Organism | Mus musculus (Mouse) |
| Length | 479 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29217618 29575903 29660268 29733200 31772009 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDETSPLVSP11ERAQPPEYTF21PSGSGAHFPQ31VPGGAVRVAA41AAGSGPSPPC
51-10051SPGHDRERQP61LLDRARGAAA71QGQTHTVAVQ81AQALAAQAAV91AAHAVQTHRE
101-150101RNDFPEDPEF111EVVVRQAEVA121IECSIYPERI131YQGSSGSYFV141KDSQGRIVAV
151-200151FKPKNEEPYG161HLNPKWTKWL171QKLCCPCCFG181RDCLVLNQGY191LSEAGASLVD
201-250201QKLELNIVPR211TKVVYLASET221FNYSAIDRVK231SRGKRLALEK241VPKVGQRFNR
251-300251IGLPPKVGSF261QLFVEGYKDA271DYWLRRFEAE281PLPENTNRQL291LLQFERLVVL
301-350301DYIIRNTDRG311NDNWLIKYDC321PMDNSSCRDT331DWVMVREPVI341KVAAIDNGLA
351-400351FPLKHPDSWR361AYPFYWAWLP371QAKVPFSQEI381KDLILPKISD391PNFIKDLEED
401-450401LYELFKRDPG411FDRGQFHKQI421AVMRGQILNL431TQALKDNKSP441LHLVQMPPVI
451-479451VETARSHQRS461ASESYTQSFQ471SRKPFFSWW
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 50 | - | - | - |
Deep-Palm: 0.96
|
|
| 123 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.80
|
|
| 174 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.97
Deep-Palm: 0.24
|
|
| 175 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.97
Deep-Palm: 0.35
|
|
| 177 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.97
Deep-Palm: 0.45
|
|
| 178 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.97
Deep-Palm: 0.54
|
|
| 183 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
|
Brain
(35358180)
|
Deep-Palm: 0.90
|
| 320 | - | - | - |
Deep-Palm: 0.03
|
|
| 327 | - | - | - |
Deep-Palm: 0.06
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
5
Liver
Specificity: 0.167
5/5 (100.0%)
3
Brain
Specificity: 0.100
3/3 (100.0%)
2
Raw 264.7
Specificity: 0.067
2/2 (100.0%)
2
Testis
Specificity: 0.067
2/2 (100.0%)
1
NSC
Specificity: 0.033
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.882
15
Brain tissue (Mass)
Specificity: 0.500
15/56 (26.8%)
2
Liver tissue (Mass)
Specificity: 0.067
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.