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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q32Q12 NME1-NME2 Nucleoside diphosphate kinase (EC 2.7.4.6) Homo sapiens (Human) 292 aa

Protein Details: Q32Q12 (NME1-NME2)

Protein Information
AccessionQ32Q12
Protein NamesNucleoside diphosphate kinase (EC 2.7.4.6)
Gene SymbolNME1-NME2
OrganismHomo sapiens (Human)
Length292 aa
IsoformsNo isoforms
Related PMIDs 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLLSTLGIV11FQGEGPPISS21CDTGTMANCE31RTFIAIKPDG41VQRGLVGEII
51-10051KRFEQKGFRL61VGLKFMQASE71DLLKEHYVDL81KDRPFFAGLV91KYMHSGPVVA
101-150101MVWEGLNVVK111TGRVMLGETN121PADSKPGTIR131GDFCIQVGRT141MANLERTFIA
151-200151IKPDGVQRGL161VGEIIKRFEQ171KGFRLVAMKF181LRASEEHLKQ191HYIDLKDRPF
201-250201FPGLVKYMNS211GPVVAMVWEG221LNVVKTGRVM231LGETNPADSK241PGTIRGDFCI
251-292251QVGRNIIHGS261DSVKSAEKEI271SLWFKPEELV281DYKSCAHDWV291YE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
21 - - -
Deep-Palm: 0.57
29 Nucleoside diphosphate kinase-like domain superfamily Nucleoside diphosphate kinase-like domain - -
GPS-Palm: 0.79
Deep-Palm: 0.76
134 SWISSPALM DBPTM CYSMODDB Nucleoside diphosphate kinase
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.83
Deep-Palm: 0.81
249 - - -
GPS-Palm: 0.82
Deep-Palm: 0.73
285 SWISSPALM DBPTM CYSMODDB - - -
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.250
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine