Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q3KNM2 | Marchf5 | E3 ubiquitin-protein ligase MARCHF5 (EC … | Mus musculus (Mouse) | 278 aa |
Protein Details: Q3KNM2 (Marchf5)
Protein Information
| Accession | Q3KNM2 |
|---|---|
| Protein Names | E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCHF5) |
| Gene Symbol | Marchf5 |
| Organism | Mus musculus (Mouse) |
| Length | 278 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPDQALQQML11DRSCWVCFAT21DEDDRTAEWV31RPCRCRGSTK41WVHQACLQRW
51-10051VDEKQRGNST61ARVACPQCNA71EYLIVFPKLG81PVVYVLDLAD91RLISKACPFA
101-150101AAGIMVGSIY111WTAVTYGAVT121VMQVVGHKEG131LDVMERADPL141FLLIGLPTIP
151-200151VMLILGKMIR161WEDYVLRLWR171KYSNKLQILN181SIFPGIGCPV191PRIPAEANPL
201-250201ADHVSATRIL211CGALVFPTIA221TIVGKLMFSS231VNSNLQRTIL241GGIAFVAIKG
251-278251AFKVYFKQQQ261YLRQAHRKIL271NYPEQEEA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 14 | RING/U-box Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-CH-type E3 UBIQUITIN-PROTEIN LIGASE MARCH5 | - | - |
Deep-Palm: 0.14
|
|
| 17 | RING/U-box Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-CH-type E3 UBIQUITIN-PROTEIN LIGASE MARCH5 | - | - |
Deep-Palm: 0.19
|
|
| 33 | RING/U-box Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-CH-type E3 UBIQUITIN-PROTEIN LIGASE MARCH5 | - | - |
Deep-Palm: 0.14
|
|
| 35 | RING/U-box Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-CH-type E3 UBIQUITIN-PROTEIN LIGASE MARCH5 | - | - |
Deep-Palm: 0.11
|
|
| 46 | E3 UBIQUITIN-PROTEIN LIGASE MARCH5 Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-CH-type RING/U-box |
brain
(39008777)
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.40
|
|
| 65 | - | - | - |
Deep-Palm: 0.49
|
|
| 68 | - | - | - |
Deep-Palm: 0.60
|
|
| 97 | - | - | - |
Deep-Palm: 0.90
|
|
| 188 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.85
|
| 211 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.200
4/4 (100.0%)
1
Brain
Specificity: 0.050
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.750
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.