Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q3TIU4 Pde12 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC … Mus musculus (Mouse) 608 aa

Protein Details: Q3TIU4 (Pde12)

Protein Information
AccessionQ3TIU4
Protein Names2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)
Gene SymbolPde12
OrganismMus musculus (Mouse)
Length608 aa
IsoformsNo isoforms
Related PMIDs 35477839 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MWRLPGRSAL11RGVRSVVERR21SRAEAGTHEA31VRAMERAVVR41CVPSEPKLSL
51-10051SFALADGSHK61NMQRDQSEPL71GRALSRIATN81ALKGHAKVAA91AKKSRKNRAH
101-150101SSGGAACEAT111GPEPVATCEP121VVKLYYREEA131VAEDVLNVDA141WQDGAVLQIG
151-200151DVKYKVERNP161PTFTELQLPR171YIMAGFPVCP181KLGVEFGDPA191SSVFRWYKEV
201-250201KPGAAEPGDS211GPASSSHSSQ221PSAWIETGVD231ERVYTPCNAD241IGLRLRLHCT
251-300251PGNGQRFGPS261RELESLCPVE271AGPGTCTFDH281RHLYTKKVTE291DSFIRTVSYN
301-350301ILADTYAQTE311FSRTVLYPYC321APYALELDYR331QNLIQKELTG341YNADLICLQE
351-400351VDRAVFSDSL361VPALEAFGLE371GVFRIKQHEG381LATFYRKSKF391RLLSQHDISF
401-450401QEALKSDPLH411KELLEKLALN421PLAQEKVLQR431SSVLQISVLQ441STTDSSKKIC
451-500451VANTHLYWHP461KGGYIRLIQM471EVALVHIRHV481SRDLYPGIPV491IFCGDFNSTP
501-550501STGMYHFVIS511GSIAEDHEDW521ASNGEEERCS531MPLSHCFKLK541SACGEPAYTN
551-600551YVGGFHGCLD561YIFIDLNTLE571VEQVIPLPSH581EEVTTHQALP591SVSHPSDHIA
601-608601LVCDLKWK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 - - -
Deep-Palm: 0.98
107 - - -
Deep-Palm: 0.93
118 - - -
Deep-Palm: 0.90
179 - - -
Deep-Palm: 0.88
237 -
MLE (39008777)
-
Deep-Palm: 0.72
249 - - -
Deep-Palm: 0.88
267 - - -
Deep-Palm: 0.85
276 - - -
Deep-Palm: 0.90
320 - - -
Deep-Palm: 0.61
347 - - -
Deep-Palm: 0.88
450 - - -
Deep-Palm: 0.46
493 - - -
Deep-Palm: 0.05
529 - - -
Deep-Palm: 0.58
536 - - -
Deep-Palm: 0.79
543 - - -
Deep-Palm: 0.33
558 - - -
Deep-Palm: 0.23
603 - - -
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.667
2/2 (100.0%)
1
Liver
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine