Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q3TWL2 | Pip4p1 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase … | Mus musculus (Mouse) | 284 aa |
Protein Details: Q3TWL2 (Pip4p1)
Protein Information
| Accession | Q3TWL2 |
|---|---|
| Protein Names | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 1 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase I) (Transmembrane protein 55B) |
| Gene Symbol | Pip4p1 |
| Organism | Mus musculus (Mouse) |
| Length | 284 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31772009 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAADGERSPL11LSEAGDGGAG21GNGLAGPGGS31ATGPGGGLTP41SAPPYGAGKH
51-10051APPQAFPPFP61EGHPAVLPGE71DPPPYSPLTS81PDSGSAPMIT91CRVCQSPINV
101-150101EGKMHQHVVK111CGVCNEATPI121KNAPPGKKYV131RCPCNCLLIC141KVTSQRIACP
151-200151RPYCKRIINL161GPVHPGPLSP171EPQPMGVRVI181CGHCKNTFLW191TEFTDRTLAR
201-250201CPHCRKVSSI211GRRYPRKRCI221CCFLLGLLLA231VTATGLAFGT241WKHAQQYGGI
251-284251YAAWAFVILL261AVLCLGRALY271WACMKVSHPV281QNFS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 91 | - | - | - |
Deep-Palm: 0.26
|
|
| 94 | - |
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.08
|
|
| 111 | - | - | - |
Deep-Palm: 0.14
|
|
| 114 | - | - | - |
Deep-Palm: 0.14
|
|
| 132 | - | - | - |
Deep-Palm: 0.68
|
|
| 134 | SWISSPALM DBPTM CYSMODDB | Transmembrane protein 55A |
Forebrain
(28680068)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.68
|
| 136 | SWISSPALM DBPTM CYSMODDB | Transmembrane protein 55A |
Forebrain
(28680068)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.80
|
| 140 | SWISSPALM DBPTM CYSMODDB | Transmembrane protein 55A |
Forebrain
(28680068)
| - |
Deep-Palm: 0.36
|
| 149 | - | - | - |
Deep-Palm: 0.37
|
|
| 154 | - | - | - |
Deep-Palm: 0.45
|
|
| 181 | - | - | - |
Deep-Palm: 0.21
|
|
| 184 | - | - | - |
Deep-Palm: 0.12
|
|
| 201 | - | - | - |
Deep-Palm: 0.35
|
|
| 204 | - | - | - |
Deep-Palm: 0.49
|
|
| 219 | - | - | - |
Deep-Palm: 0.96
|
|
| 221 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.96
|
|
| 222 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.98
|
|
| 264 | - | - | - |
Deep-Palm: 0.90
|
|
| 273 | - | - | - |
Deep-Palm: 0.18
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
2
Liver
Specificity: 0.154
2/2 (100.0%)
2
Testis
Specificity: 0.154
2/2 (100.0%)
1
Brain
Specificity: 0.077
1/1 (100.0%)
1
NSC
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Brain tissue (Mass)
Specificity: 0.385
5/56 (8.9%)
1
Liver tissue (Mass)
Specificity: 0.077
1/8 (12.5%)
1
Neural Stem Cells (Mass)
Specificity: 0.077
1/1 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.