Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q3UUI3 | Them4 | Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA … | Mus musculus (Mouse) | 230 aa |
Protein Details: Q3UUI3 (Them4)
Protein Information
| Accession | Q3UUI3 |
|---|---|
| Protein Names | Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Carboxyl-terminal modulator protein) (Thioesterase superfamily member 4) |
| Gene Symbol | Them4 |
| Organism | Mus musculus (Mouse) |
| Length | 230 aa |
| Isoforms | No isoforms |
| Related PMIDs | 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRNCAMRLR11TLGATPARRP21GAARRLFSSE31KVIRKDYALP41NPSWTKDLRL
51-10051LFDQFMKKCE61DGSWKRMPSH71RQNPTRAIQE81FQTLFVDSKF91KKEEQMSKAQ
101-150101QFTRSFEEGL111GFEYAMFYNK121VEKRTVSLFQ131GGLHLQGVPG141FVHGGAIATI
151-200151IDVTTGTCAI161SEGVAMTANL171NITYKKPIPL181LSVVVVNSQL191QKIEGRKLFV
201-230201SCTIQSIDEK211TLYTEATALF221IKLDPEKPLT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.04
|
|
| 59 | - | - | - |
Deep-Palm: 0.30
|
|
| 158 | - | - | - |
Deep-Palm: 0.72
|
|
| 202 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.92
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.095
2/2 (100.0%)
1
Brain
Specificity: 0.048
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.857
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.