Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q3V3R1 | Mthfd1l | Monofunctional C1-tetrahydrofolate synthase, mitochondrial (EC … | Mus musculus (Mouse) | 977 aa |
Protein Details: Q3V3R1 (Mthfd1l)
Protein Information
| Accession | Q3V3R1 |
|---|---|
| Protein Names | Monofunctional C1-tetrahydrofolate synthase, mitochondrial (EC 6.3.4.3) (Formyltetrahydrofolate synthetase) |
| Gene Symbol | Mthfd1l |
| Organism | Mus musculus (Mouse) |
| Length | 977 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29217618 29660268 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSVRLPLLLR11QLGRQQLPSG21PACRLRELCR31SGSRSSSSGG41GDPEGLRGRR
51-10051LQDGQTFSSH61GPGNPEAPGM71DSIVRDVIHN81SKEVLSLLQE91KNPAFKPVLV
101-150101VIQAGDDNLM111KDMNQNLAKE121AGLDITHICL131PPDSGEDEII141DEILKINEDP
151-200151RVHGLTLQIS161EDSLSNKVLN171ALKPEKDVDG181VTDINLGKLV191RGDAPECFVS
201-250201PLAKAAVELV211EKSGITLDGK221KVLVVGAHGP231LEAALQWLFQ241RKGSMTMSCP
251-300251WATPQLPDKL261READIVVLGS271PKPEEIPAVW281IPSGTTILNC291FHDFLSGKLS
301-350301GGSPGVPVDK311LIAEESVSLL321AAALRIQNMV331SSGRRWLREQ341QHRRWRLHCL
351-400351KLQPLSPVPS361DIEISRGQTP371KAVDVLAKEI381GLLADEIEIY391GKSKAKVQLS
401-450401LLERLKDQTD411GKYVLVAGIT421PTPLGEGKST431VTIGLVQALT441AHLKVNSFAC
451-500451LRQPSQGPTF461GVKGGAAGGG471YAQVIPMEEF481NLHLTGDIHA491ITAANNLLAA
501-550501AIDTRILHES511TQTDKALYNR521LVPLVNGVRE531FSEIQLSRLK541KLGIHKTDPS
551-600551TLTEEEVRKF561ARLNIDPATI571TWQRVLDTND581RFLRKITIGQ591GSTEKGYSRQ
601-650601AQFDIAVASE611IMAVLALTDS621LTDMKERLGR631MVVASDKDGQ641PVTAEDLGVT
651-700651GALTVLMKDA661IKPNLMQTLE671GTPVFVHAGP681FANIAHGNSS691VLADKIALKL
701-750701VGEEGFVVTE711AGFGADIGME721KFFNIKCRAS731GLVPNVVVLV741ATVRALKMHG
751-800751GGPSVTAGVP761LKKEYTEENI771QLVADGCCNL781QKQIQIAQLF791GVPVVVALNV
801-850801FKTDTRAEID811LVCELAKRAG821AFDAVPCYHW831SAGGKGSVDL841ARAVREAANK
851-900851RSRFQFLYDV861QLPIVEKIRV871IAQTVYGAKD881IELSPEAQSK891IDRYTQQGFG
901-950901NLPICMAKTH911LSLSHEPDKK921GVPRDFTLPI931SDVRASIGAG941FIYPLVGTMS
951-977951TMPGLPTRPC961FYDIDLDTET971EQVKGLF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 23 | - | - | - |
Deep-Palm: 0.98
|
|
| 29 | - | - | - |
Deep-Palm: 0.97
|
|
| 129 | - | - | - |
Deep-Palm: 0.97
|
|
| 197 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 249 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
| - |
Deep-Palm: 0.82
|
| 290 | - | - | - |
Deep-Palm: 0.71
|
|
| 349 | - | - | - |
Deep-Palm: 0.83
|
|
| 450 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.93
|
|
| 727 | - | - | - |
Deep-Palm: 0.76
|
|
| 777 | - | - | - |
Deep-Palm: 0.40
|
|
| 778 | - | - | - |
Deep-Palm: 0.35
|
|
| 813 | Formate--tetrahydrofolate ligase |
MLE
(39008777)
| - |
GPS-Palm: 0.91
Deep-Palm: 0.95
|
|
| 827 | - | - | - |
Deep-Palm: 0.96
|
|
| 905 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.78
|
|
| 960 | - | - | - |
Deep-Palm: 0.59
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
Brain
Specificity: 0.250
2/2 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.375
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.