Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q53QD5 | HSPD1 | 60 kDa heat shock protein, … | Homo sapiens (Human) | 55 aa |
Protein Details: Q53QD5 (HSPD1)
Protein Information
| Accession | Q53QD5 |
|---|---|
| Protein Names | 60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (Heat shock protein 60) |
| Gene Symbol | HSPD1 |
| Organism | Homo sapiens (Human) |
| Length | 55 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 22496122 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501QKCEFQDAYV11LLSEKKISSI21QSIVPALEIA31NAHRKPLVII41AEDVDGEALS
51-5551TLVLN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | GroEL-like apical domain superfamily | - |
LNCaP
(31251020)
Unknown
(32651440)
|
GPS-Palm: 0.84
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.167
1/1 (100.0%)
1
EC cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 362 | G → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 370 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 370 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 370 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |