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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q53XL8 PSMC1; hCG_2029049 26S proteasome regulatory subunit 4 … Homo sapiens (Human) 440 aa

Protein Details: Q53XL8 (PSMC1)

Protein Information
Accession Q53XL8
Protein Names 26S proteasome regulatory subunit 4 (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene Symbol PSMC1; hCG_2029049
Organism Homo sapiens (Human)
Length 440 aa
Isoforms No isoforms
Related PMIDs 19137006
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
6
Jurkat T cells
Specificity: 1.000
6/25 (24.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGQSQSGGHG11PGGGKKDDKD21KKKKYEPPVP31TRVGKKKKKT41KGPDAASKLP
51-10051LVTPHTQCRL61KLLKLERIKD71YLLMEEEFIR81NQEQMKPLEE91KQEEERSKVD
101-150101DLRGTPMSVG111TLEEIIDDNH121AIVSTSVGSE131HYVSILSFVD141KDLLEPGCSV
151-200151LLNHKVHAVI161GVLMDDTDPL171VTVMKVEKAP181QETYADIGGL191DNQIQEIKES
201-250201VELPLTHPEY211YEEMGIKPPK221GVILYGPPGT231GKTLLAKAVA241NQTSATFLRV
251-300251VGSELIQKYL261GDGPKLVREL271FRVAEEHAPS281IVFIDEIDAI291GTKRYDSNSG
301-350301GEREIQRTML311ELLNQLDGFD321SRGDVKVIMA331TNRIETLDPA341LIRPGRIDRK
351-400351IEFPLPDEKT361KKRIFQIHTS371RMTLADDVTL381DDLIMAKDDL391SGADIKAICT
401-440401EAGLMALRER411RMKVTNEDFK421KSKENVLYKK431QEGTPEGLYL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
58 Prediction (High) - -
399 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
137 S → Cfs*28 0.010870 DEL Frame Shift Del ACC
363 R → C 0.007299 SNP Missense Mutation READ
410 R → C 0.002288 SNP Missense Mutation STAD