Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q543P6 Acot11 Acyl-coenzyme A thioesterase 11 (EC … Mus musculus (Mouse) 594 aa

Protein Details: Q543P6 (Acot11)

Protein Information
AccessionQ543P6
Protein NamesAcyl-coenzyme A thioesterase 11 (EC 3.1.2.2) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (Palmitoyl-coenzyme A thioesterase)
Gene SymbolAcot11
OrganismMus musculus (Mouse)
Length594 aa
IsoformsNo isoforms
Related PMIDs 29660268 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MIQNVGNHLR11RGFASMFSNR21TSRKSISHPE31SGDPPTMAEG41EGYRNPTEVQ
51-10051MSQLVLPCHT61NHRGELSIGQ71LLKWIDTTAC81LSAERHAGCP91CVTASMDDIY
101-150101FDHTISVGQV111VNIKAKVNRA121FNSSMEVGIQ131VVSEDLCSEK141QWSVCKALAT
151-200151FVAHRELSKV161KLKQVIPLTE171EEKTEHGVAA181ERRRMRLVYA191DTIKDLLTHC
201-250201VIQDDLDKDC211SNMVPAEKTR221VESVELVLPP231HANHQGNTFG241GQIMAWMENV
251-300251ATIAASRLCH261AHPTLKAIEM271FHFRGPSQVG281DRLVLKAIVN291NAFKHSMEVG
301-350301VCVEAYRQEA311ETQRRHINSA321FMTFVVLDKD331DQPQKLPWIR341PQPGEGERRY
351-400351REASARKKIR361LDRKYLVSCK371QAEVALSVPW381DPSNQVYLSY391YNVSSLKTLM
401-450401AKDNWVLSVE411ISEVRLYILE421EDFLSFHLEM431VVNVDAAQVF441QLLSDLRRRP
451-500451EWDKHYRSVE461LVQQVDEDDA471IYHVISPALS481GNTKPQDFVI491LASRRKPCDN
501-550501GDPYVIALRS511VTLPTHHETP521EYQRGETLCS531GFCLWREGDQ541MTKVSYYNQA
551-594551TPGFLNYVTT561NVSGLSSEFY571NTFKACESFL581LDNRNDLAPS591LQTL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
58 - - -
GPS-Palm: 0.68
Deep-Palm: 0.96
80 - - -
GPS-Palm: 0.88
Deep-Palm: 0.96
89 - - -
Deep-Palm: 0.09
91 - - -
Deep-Palm: 0.11
137 - - -
Deep-Palm: 0.64
145 - - -
Deep-Palm: 0.94
200 - -
Brain (35358180)
Deep-Palm: 0.54
210 - - -
Deep-Palm: 0.60
259 - - -
GPS-Palm: 0.74
Deep-Palm: 0.35
302 - - -
Deep-Palm: 0.42
369 - - -
GPS-Palm: 0.80
Deep-Palm: 0.96
498 - - -
GPS-Palm: 0.67
Deep-Palm: 0.87
529 - - -
GPS-Palm: 0.67
Deep-Palm: 0.54
533 - - -
GPS-Palm: 0.90
Deep-Palm: 0.70
576 - - -
GPS-Palm: 0.91
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Brain
Specificity: 0.056
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
17
Brain tissue (Mass)
Specificity: 0.944
17/56 (30.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine