Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q562R1 | ACTBL2 | Beta-actin-like protein 2 (Kappa-actin) | Homo sapiens (Human) | 376 aa |
Protein Details: Q562R1 (ACTBL2)
Protein Information
| Accession | Q562R1 |
|---|---|
| Protein Names | Beta-actin-like protein 2 (Kappa-actin) |
| Gene Symbol | ACTBL2 |
| Organism | Homo sapiens (Human) |
| Length | 376 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 33636221 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTDNELSALV11VDNGSGMCKA21GFGGDDAPRA31VFPSMIGRPR41HQGVMVGMGQ
51-10051KDCYVGDEAQ61SKRGVLTLKY71PIEHGVVTNW81DDMEKIWYHT91FYNELRVAPD
101-150101EHPILLTEAP111LNPKINREKM121TQIMFEAFNT131PAMYVAIQAV141LSLYASGRTT
151-200151GIVMDSGDGV161THIVPIYEGY171ALPHAILRLD181LAGRDLTDYL191MKILTERGYN
201-250201FTTTAEREIV211RDVKEKLCYV221ALDFEQEMVR231AAASSSPERS241YELPDGQVIT
251-300251IGNERFRCPE261AIFQPSFLGI271ESSGIHETTF281NSIMKCDVDI291RKDLYANTVL
301-350301SGGSTMYPGI311ADRMQKEIIT321LAPSTMKIKI331IAPPERKYSV341WIGGSILASL
351-376351STFQQMWISK361QEYDEAGPPI371VHRKCF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 18 | ATPase, nucleotide binding domain Actin family | - | - |
Deep-Palm: 0.93
|
|
| 53 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.83
|
|
| 218 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.95
|
|
| 258 | - | - | - |
Deep-Palm: 0.81
|
|
| 286 | SWISSPALM DBPTM CYSMODDB | Actin | - | - |
Deep-Palm: 0.30
|
| 375 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
PC3
Specificity: 0.667
2/2 (100.0%)
1
heart
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 96 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 219 | Y → C | 0.007299 | SNP | Missense Mutation | READ |
| 255 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 286 | C → C | 0.002506 | SNP | Silent | COAD |
| 291 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |