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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q5BKV1 MYH9 MYH9 protein (Myosin heavy chain … Homo sapiens (Human) 218 aa

Protein Details: Q5BKV1 (MYH9)

Protein Information
AccessionQ5BKV1
Protein NamesMYH9 protein (Myosin heavy chain 9)
Gene SymbolMYH9
OrganismHomo sapiens (Human)
Length218 aa
IsoformsNo isoforms
Related PMIDs 29575903 31251020 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAQQAADKYL11YVDKNFINNP21LAQADWAAKK31LVWVPSDKSG41FEPASLKEEV
51-10051GEEAIVELVE61NGKKVKVNKD71DIQKMNPPKF81SKVEDMAELT91CLNEASVLHN
101-150101LKERYYSGLI111YTYSGLFCVV121INPYKNLPIY131SEEIVEMYKG141KKRHEMPPHI
151-200151YAITDTAYRS161MMQDREDQSI171LCTGESGAGK181TENTKKVIQY191LAYVASSHKS
201-218201KKDQEAYFKN211RAVRLGVL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
91 - -
LNCaP (31251020)
Unknown (32651440)
GPS-Palm: 0.76
Deep-Palm: 0.81
118 - - -
Deep-Palm: 0.26
172 SWISSPALM DBPTM CYSMODDB Myosin head (motor domain)
HeLa (29575903)
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.79
Deep-Palm: 0.78
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
cerebral cortex
Specificity: 0.500
4/4 (100.0%)
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
1
HeLa cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
91 C → Y 0.002506 SNP Missense Mutation COAD
104 R → C 0.002506 SNP Missense Mutation COAD
172 C → Lfs*4 0.001969 INS Frame Shift Ins HNSC
172 C → Y 0.001887 SNP Missense Mutation UCEC
240 R → C 0.001887 SNP Missense Mutation UCEC
263 R → C 0.006944 SNP Missense Mutation TGCT
263 R → C 0.002545 SNP Missense Mutation GBM
282 S → C 0.001764 SNP Missense Mutation LUAD
393 R → C 0.002288 SNP Missense Mutation STAD
427 R → C 0.002141 SNP Missense Mutation SKCM
573 Y → C 0.001014 SNP Missense Mutation BRCA
764 R → C 0.001014 SNP Missense Mutation BRCA
789 C → C 0.001887 SNP Silent UCEC
816 C → C 0.002288 SNP Silent STAD
905 R → C 0.002141 SNP Missense Mutation SKCM
1114 S → C 0.001014 SNP Missense Mutation BRCA
1114 S → C 0.002033 SNP Missense Mutation LUSC
1268 R → C 0.001887 SNP Missense Mutation UCEC
1520 V → Cfs*137 0.002033 INS Frame Shift Ins LUSC
1652 R → C 0.002288 SNP Missense Mutation STAD
1697 R → C 0.002506 SNP Missense Mutation COAD
1697 R → C 0.002020 SNP Missense Mutation PRAD
1732 A → _Q1733insCLLQKIHS 0.002033 INS In Frame Ins LUSC
1743 G → C 0.001764 SNP Missense Mutation LUAD
1838 R → C 0.001764 SNP Missense Mutation LUAD
1838 R → C 0.001887 SNP Missense Mutation UCEC
1912 R → C 0.001887 SNP Missense Mutation UCEC