Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5H936 | SERINC3 | Serine incorporator 3 | Homo sapiens (Human) | 212 aa |
Protein Details: Q5H936 (SERINC3)
Protein Information
| Accession | Q5H936 |
|---|---|
| Protein Names | Serine incorporator 3 |
| Gene Symbol | SERINC3 |
| Organism | Homo sapiens (Human) |
| Length | 212 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.929
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.929
13/46 (28.3%)
1
PC3 cells
Specificity: 0.071
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501EHQPRSGLLQ11SSLITLYTMY21LTWSAMSNEP31DRSCNPNLMS41FITRITAPTL
51-10051APGNSTAVVP61TPTPPSKSGS71LLDSDNFIGL81FVFVLCLLYS91SIRTSTNSQV
101-150101DKLTLSGSDS111VILGDTTTSG121ASDEEDGQPR131RAVDNEKEGV141QYSYSLFHLM
151-200151LCLASLYIMM161TLTSWYSPDA171KFQSMTSKWP181AVWVKISSSW191VCLLLYVWTL
201-212201VAPLVLTSRD211FS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 34 | CYSMODDB SWISSPALM DBPTM | Serine incorporator (Serinc) | - |
| 86 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 148 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 148 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 190 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 248 | C → C | 0.002506 | SNP | Silent | COAD |
| 248 | C → C | 0.002020 | SNP | Silent | PRAD |
| 293 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 293 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 338 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 354 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 354 | R → C | 0.027027 | SNP | Missense Mutation | DLBC |
| 403 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |