Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q5JP53 TUBB Tubulin beta chain Homo sapiens (Human) 426 aa

Protein Details: Q5JP53 (TUBB)

Protein Information
Accession Q5JP53
Protein Names Tubulin beta chain
Gene Symbol TUBB
Organism Homo sapiens (Human)
Length 426 aa
Isoforms No isoforms
Related PMIDs 21076176 31251020 31382980 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.706
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.706
36/46 (78.3%)
6
Jurkat T cells
Specificity: 0.118
6/25 (24.0%)
4
PC3 cells
Specificity: 0.078
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.078
4/4 (100.0%)
1
U937 cells
Specificity: 0.020
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFWEVISDEH11GIDPTGTYHG21DSDLQLDRIS31VYYNEATGGK41YVPRAILVDL
51-10051EPGTMDSVRS61GPFGQIFRPD71NFVFGQSGAG81NNWAKGHYTE91GAELVDSVLD
101-150101VVRKEAESCD111CLQGFQLTHS121LGGGTGSGMG131TLLISKIREE141YPDRIMNTFS
151-200151VVPSPKVSDT161VVEPYNATLS171VHQLVENTDE181TYCIDNEALY191DICFRTLKLT
201-250201TPTYGDLNHL211VSATMSGVTT221CLRFPGQLNA231DLRKLAVNMV241PFPRLHFFMP
251-300251GFAPLTSRGS261QQYRALTVPE271LTQQVFDAKN281MMAACDPRHG291RYLTVAAVFR
301-350301GRMSMKEVDE311QMLNVQNKNS321SYFVEWIPNN331VKTAVCDIPP341RGLKMAVTFI
351-400351GNSTAIQELF361KRISEQFTAM371FRRKAFLHWY381TGEGMDEMEF391TEAESNMNDL
401-426401VSEYQQYQDA411TAEEEEDFGE421EAEEEA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
109 Prediction (Low) - -
193 Prediction (Medium) - -
221 Prediction (High) - -
285 Prediction (High) - -
336 CYSMODDB SWISSPALM DBPTM Prediction (High) Tubulin C-terminal domain -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
233 M → Cfs*14 0.002976 DEL Frame Shift Del KIRC
251 R → C 0.001887 SNP Missense Mutation UCEC