Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5JR49 | SLC7A1 | Solute carrier family 7 member … | Homo sapiens (Human) | 121 aa |
Protein Details: Q5JR49 (SLC7A1)
Protein Information
| Accession | Q5JR49 |
|---|---|
| Protein Names | Solute carrier family 7 member 1 |
| Gene Symbol | SLC7A1 |
| Organism | Homo sapiens (Human) |
| Length | 121 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCKVLLNIG11QQMLRRKVVD21CSREETRLSR31CLNTFDLVAL41GVGSTLGAGV
51-10051YVLAGAVARE61NAGPAIVISF71LIAALASVLA81GLCYGEFGAR91VPKTGSAYLY
101-121101SYVTVGELWA111FITGWNLILS121Y
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
| 21 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.88
|
|
| 31 | INNER MEMBRANE TRANSPORTER YGJI-RELATED | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.96
|
|
| 83 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
LNCaP
Specificity: 0.444
4/4 (100.0%)
3
PC3
Specificity: 0.333
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP cells (Mass)
Specificity: 0.222
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 59 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 232 | C → G | 0.002294 | SNP | Missense Mutation | OV |
| 302 | F → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 501 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |