Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5JR94 | RPS8 | 40S ribosomal protein S8 | Homo sapiens (Human) | 208 aa |
Protein Details: Q5JR94 (RPS8)
Protein Information
| Accession | Q5JR94 |
|---|---|
| Protein Names | 40S ribosomal protein S8 |
| Gene Symbol | RPS8 |
| Organism | Homo sapiens (Human) |
| Length | 208 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGISRDNWHK11RRKTGGKRKP21YHKKRKYELG31RPAANTKIGP41RRIHTVRVRG
51-10051GNKKYRALRL61DVGNFSWGSE71CCTRKTRIID81VVYNASNNEL91VRTKTLVKNC
101-150101IVLIDSTPYR111QWYESHYALP121LGRKKGAKLT131PEEEEILNKK141RSKKIQKKYD
151-200151ERKKNAKISS161LLEEQFQQGK171LLACIASRPG181QCGRADGYVL191EGKELEFYLR
201-208201KIKARKGK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 71 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.91
Deep-Palm: 0.88
|
|
| 72 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.91
Deep-Palm: 0.74
|
|
| 100 | - | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.91
Deep-Palm: 0.80
|
|
| 174 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.80
Deep-Palm: 0.98
|
|
| 182 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.70
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
2
PC3
Specificity: 0.250
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Cerebral Cortex (Mass)
Specificity: 0.375
3/4 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 71 | C → W | 0.001014 | SNP | Missense Mutation | BRCA |
| 74 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 123 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 182 | C → C | 0.002288 | SNP | Silent | STAD |