Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5STU3 | DDX39B | RNA helicase (EC 3.6.4.13) | Homo sapiens (Human) | 425 aa |
Protein Details: Q5STU3 (DDX39B)
Protein Information
| Accession | Q5STU3 |
|---|---|
| Protein Names | RNA helicase (EC 3.6.4.13) |
| Gene Symbol | DDX39B |
| Organism | Homo sapiens (Human) |
| Length | 425 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.917
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.917
33/46 (71.7%)
3
Cerebral cortex
Specificity: 0.083
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAENDVDNEL11LDYEDDEVET21AAGGDGAEAP31AKKDVKGSYV41SIHSSGFRDF
51-10051LLKPELLRAI61VDCGFEHPSE71VQHECIPQAI81LGMDVLCQAK91SGMGKTAVFV
101-150101LATLQQLEPV111TGQVSVLVMC121HTRELAFQIS131KEYERFSKYM141PNVKVAVFFG
151-200151GLSIKKDEEV161LKKNCPHIVV171GTPGRILALA181RNKSLNLKHI191KHFILDECDK
201-250201MLEQLDMRRD211VQEIFRMTPH221EKQVMMFSAT231LSKEIRPVCR241KFMQDPMEIF
251-300251VDDETKLTLH261GLQQYYVKLK271DNEKNRKLFD281LLDVLEFNQV291VIFVKSVQRC
301-350301IALAQLLVEQ311NFPAIAIHRG321MPQEERLSRY331QQFKDFQRRI341LVATNLFGRG
351-400351MDIERVNIAF361NYDMPEDSDT371YLHRCYPLSP381SRWPEQAGLA391PRAWLSHLCP
401-425401MRMMPRSSMM411CRIALRSILV421SCLMR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 63 | Prediction (Low) | - | - |
| 87 | Prediction (Medium) | - | - |
| 120 | Prediction (Low) | - | - |
| 165 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | - |
| 239 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | - |
| 300 | Prediction (Medium) | - | - |
| 399 | Prediction (Low) | - | - |
| 411 | Prediction (Medium) | - | - |
| 422 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 216 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 250 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 296 | S → C | 0.002020 | SNP | Missense Mutation | PRAD |