Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5SY01 | PAFAH2 | 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) | Homo sapiens (Human) | 165 aa |
Protein Details: Q5SY01 (PAFAH2)
Protein Information
| Accession | Q5SY01 |
|---|---|
| Protein Names | 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) |
| Gene Symbol | PAFAH2 |
| Organism | Homo sapiens (Human) |
| Length | 165 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGVNQSVGFP11PVTGPHLVGC21GDVMEGQNLQ31GSFFRLFYPC41QKAEETMEQP
51-10051LWIPRYEYCT61GLAEYLQFNK71RCGGLLFNLA81VGSCRLPVSW91NGPFKTKDSG
101-150101YPLIIFSHGL111GAFRTLYSAF121CMELASRGFV131VAVPEHRDRS141AATTYFCKQA
151-165151PEENQPTNES161LQEEW
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 20 | Platelet-activating factor acetylhydrolase, isoform II Alpha/Beta hydrolase fold PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | - | - |
Deep-Palm: 0.80
|
|
| 40 | Platelet-activating factor acetylhydrolase, isoform II Alpha/Beta hydrolase fold PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | - | - |
Deep-Palm: 0.50
|
|
| 59 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.37
|
|
| 72 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.84
|
|
| 84 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.92
|
|
| 121 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.97
|
|
| 147 | - | - | - |
Deep-Palm: 0.47
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
LNCaP
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 72 | C → C | 0.001887 | SNP | Silent | UCEC |
| 85 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 169 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |