Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5T0G3 | LRRC1 | Leucine rich repeat containing 1 | Homo sapiens (Human) | 154 aa |
Protein Details: Q5T0G3 (LRRC1)
Protein Information
| Accession | Q5T0G3 |
|---|---|
| Protein Names | Leucine rich repeat containing 1 |
| Gene Symbol | LRRC1 |
| Organism | Homo sapiens (Human) |
| Length | 154 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MFHCIPLWRC11NRHVESIDKR21HCSLVYVPEE31IYRYARSLEE41LLLDANQLRE
51-10051LPEQFFQLVK61LRKLGLSDNE71IQRLPPEIAN81FMQLVELDVS91RNEIPEIPES
101-150101ISFCKALQVA111DFSGNPLTRL121PESFPELQNL131TCLSVNDISL141QSLPENIGKQ
151-154151KTTS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | SWISSPALM DBPTM CYSMODDB | Synaptic Scaffolding LAP/MAGUK Families | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.01
|
| 10 | Synaptic Scaffolding LAP/MAGUK Families | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.02
|
|
| 22 | Synaptic Scaffolding LAP/MAGUK Families | - | - |
Deep-Palm: 0.31
|
|
| 104 | - | - | - |
Deep-Palm: 0.91
|
|
| 132 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
LNCaP
Specificity: 0.364
4/4 (100.0%)
4
PC3
Specificity: 0.364
4/4 (100.0%)
2
HeLa cell
Specificity: 0.182
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.091
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 34 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 341 | C → R | 0.002033 | SNP | Missense Mutation | LUSC |
| 431 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |