Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q5T280 SPOUT1 28S rRNA (uridine-N(3))-methyltransferase (EC 2.1.1.-) … Homo sapiens (Human) 376 aa

Protein Details: Q5T280 (SPOUT1)

Protein Information
AccessionQ5T280
Protein Names28S rRNA (uridine-N(3))-methyltransferase (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (Methyltransferase C9orf114) (Ribosomal RNA methyltransferase SPOUT1) (SPOUT domain-containing methyltransferase 1)
Gene SymbolSPOUT1
OrganismHomo sapiens (Human)
Length376 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAERGRKRPC11GPGEHGQRIE21WRKWKQQKKE31EKKKWKDLKL41MKKLERQRAQ
51-10051EEQAKRLEEE61EAAAEKEDRG71RPYTLSVALP81GSILDNAQSP91ELRTYLAGQI
101-150101ARACAIFCVD111EIVVFDEEGQ121DAKTVEGEFT131GVGKKGQACV141QLARILQYLE
151-200151CPQYLRKAFF161PKHQDLQFAG171LLNPLDSPHH181MRQDEESEFR191EGIVVDRPTR
201-250201PGHGSFVNCG211MKKEVKIDKN221LEPGLRVTVR231LNQQQHPDCK241TYHGKVVSSQ
251-300251DPRTKAGLYW261GYTVRLASCL271SAVFAEAPFQ281DGYDLTIGTS291ERGSDVASAQ
301-350301LPNFRHALVV311FGGLQGLEAG321ADADPNLEVA331EPSVLFDLYV341NTCPGQGSRT
351-376351IRTEEAILIS361LAALQPGLIQ371AGARHT
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
10 - - -
GPS-Palm: 0.88
Deep-Palm: 0.04
104 - - -
GPS-Palm: 0.80
Deep-Palm: 0.84
108 - - -
GPS-Palm: 0.68
Deep-Palm: 0.74
139 - - -
GPS-Palm: 0.91
Deep-Palm: 0.92
151 - - -
GPS-Palm: 0.93
Deep-Palm: 0.91
209 - - -
GPS-Palm: 0.87
Deep-Palm: 0.67
239 - - -
Deep-Palm: 0.27
269 - - -
Deep-Palm: 0.89
343 - - -
GPS-Palm: 0.82
Deep-Palm: 0.86
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine