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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q5T7N0 RPL5 Large ribosomal subunit protein uL18 … Homo sapiens (Human) 130 aa

Protein Details: Q5T7N0 (RPL5)

Protein Information
AccessionQ5T7N0
Protein NamesLarge ribosomal subunit protein uL18 (60S ribosomal protein L5)
Gene SymbolRPL5
OrganismHomo sapiens (Human)
Length130 aa
IsoformsNo isoforms
Related PMIDs 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MIVRVTNRDI11ICQIAYARIE21GDMIVCAAYA31HELPKYGVKV41GLTNYAAAYC
51-10051TGLLLARRLL61NRFGMDKIYE71GQVEVTGDEY81NVESIDGQPG91AFTCYLDAGL
101-130101ARTTTGNKVF111GALKGAVDGG121LSIPHSTKRF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
12 SWISSPALM DBPTM CYSMODDB Translational machinery components Ribosomal large subunit proteins 60S L5 and 50S L18 Large ribosomal subunit protein uL18 eukaryotic/archaeal
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.91
Deep-Palm: 0.04
26 Ribosomal L18 L5e Translational machinery components Large ribosomal subunit protein uL18 eukaryotic/archaeal -
Unknown (32651440)
GPS-Palm: 0.70
Deep-Palm: 0.84
50 SWISSPALM DBPTM CYSMODDB Large ribosomal subunit protein uL18 eukaryotic/archaeal Ribosomal large subunit proteins 60S L5 and 50S L18 -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.91
Deep-Palm: 0.97
94 - - -
Deep-Palm: 0.83
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 0.600
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.400
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
54 R → C 0.001014 SNP Missense Mutation BRCA
54 R → C 0.006424 SNP Missense Mutation SKCM
62 C → Y 0.002545 SNP Missense Mutation GBM
100 C → F 0.004219 SNP Missense Mutation SARC
113 F → C 0.002141 SNP Missense Mutation SKCM
137 G → C 0.001887 SNP Missense Mutation UCEC
144 C → C 0.001887 SNP Silent UCEC
? ? → ? 0.002427 SNP Missense Mutation BLCA