Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5T7N0 | RPL5 | Large ribosomal subunit protein uL18 … | Homo sapiens (Human) | 130 aa |
Protein Details: Q5T7N0 (RPL5)
Protein Information
| Accession | Q5T7N0 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL18 (60S ribosomal protein L5) |
| Gene Symbol | RPL5 |
| Organism | Homo sapiens (Human) |
| Length | 130 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 29575903 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.783
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.783
36/46 (78.3%)
4
Jurkat T cells
Specificity: 0.087
4/25 (16.0%)
3
PC3 cells
Specificity: 0.065
3/4 (75.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
HeLa cells
Specificity: 0.022
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIVRVTNRDI11ICQIAYARIE21GDMIVCAAYA31HELPKYGVKV41GLTNYAAAYC
51-10051TGLLLARRLL61NRFGMDKIYE71GQVEVTGDEY81NVESIDGQPG91AFTCYLDAGL
101-130101ARTTTGNKVF111GALKGAVDGG121LSIPHSTKRF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 12 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Ribosomal large subunit proteins 60S L5 and 50S L18 | - |
| 26 | Prediction (Low) | - | - |
| 50 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Ribosomal large subunit proteins 60S L5 and 50S L18 | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 54 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 54 | R → C | 0.006424 | SNP | Missense Mutation | SKCM |
| 62 | C → Y | 0.002545 | SNP | Missense Mutation | GBM |
| 100 | C → F | 0.004219 | SNP | Missense Mutation | SARC |
| 113 | F → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 137 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 144 | C → C | 0.001887 | SNP | Silent | UCEC |
| ? | ? → ? | 0.002427 | SNP | Missense Mutation | BLCA |