Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5T8U5 | SURF4 | Surfeit locus protein 4 | Homo sapiens (Human) | 186 aa |
Protein Details: Q5T8U5 (SURF4)
Protein Information
| Accession | Q5T8U5 |
|---|---|
| Protein Names | Surfeit locus protein 4 |
| Gene Symbol | SURF4 |
| Organism | Homo sapiens (Human) |
| Length | 186 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGQNDLMGTA11EDFADQFLRV21TKQYLPHVAR31LCLISTFLED41GIRMWFQWSE
51-10051QRDYIDTTWN61CGYLLASSFV71FLNLLGQLTG81CVLVLSRNFV91QYACFGLFGI
101-150101IALQTIAYSI111LWDLKFLMRN121LALGGGLLLL131LAESRSEGKS141MFAGVPTMRE
151-186151SSPKQYMQLG161GRVLLVLMFM171TLLHFDASFF181SQPSQQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 32 | SWISSPALM DBPTM CYSMODDB | Surfeit locus 4 SURF4 family | - |
LNCaP
(31251020)
Unknown
(32651440)
|
GPS-Palm: 0.88
Deep-Palm: 0.97
|
| 61 | - | - | - |
Deep-Palm: 0.32
|
|
| 81 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.96
|
|
| 94 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.73
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
3
PC3
Specificity: 0.375
3/3 (100.0%)
2
LNCaP
Specificity: 0.250
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.250
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.125
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 30 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 52 | R → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 81 | C → C | 0.005013 | SNP | Silent | COAD |