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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q5T8U5 SURF4; RP11-244N20.4-004 Surfeit locus protein 4 Homo sapiens (Human) 186 aa

Protein Details: Q5T8U5 (SURF4)

Protein Information
Accession Q5T8U5
Protein Names Surfeit locus protein 4
Gene Symbol SURF4; RP11-244N20.4-004
Organism Homo sapiens (Human)
Length 186 aa
Isoforms No isoforms
Related PMIDs 19801377 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.786
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.786
22/46 (47.8%)
3
PC3 cells
Specificity: 0.107
3/4 (75.0%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
1
HeLa cells
Specificity: 0.036
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGQNDLMGTA11EDFADQFLRV21TKQYLPHVAR31LCLISTFLED41GIRMWFQWSE
51-10051QRDYIDTTWN61CGYLLASSFV71FLNLLGQLTG81CVLVLSRNFV91QYACFGLFGI
101-150101IALQTIAYSI111LWDLKFLMRN121LALGGGLLLL131LAESRSEGKS141MFAGVPTMRE
151-186151SSPKQYMQLG161GRVLLVLMFM171TLLHFDASFF181SQPSQQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
32 CYSMODDB SWISSPALM DBPTM Prediction (Medium) SURF4 family -
81 Prediction (Medium) - -
94 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
19 R → C 0.002141 SNP Missense Mutation SKCM
30 R → C 0.001887 SNP Missense Mutation UCEC
52 R → C 0.002976 SNP Missense Mutation KIRC
81 C → C 0.005013 SNP Silent COAD