Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5TBN3 | LCP1 | Lymphocyte cytosolic protein 1 | Homo sapiens (Human) | 246 aa |
Protein Details: Q5TBN3 (LCP1)
Protein Information
| Accession | Q5TBN3 |
|---|---|
| Protein Names | Lymphocyte cytosolic protein 1 |
| Gene Symbol | LCP1 |
| Organism | Homo sapiens (Human) |
| Length | 246 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MARGSVSDEE11MMELREAFAK21VDTDGNGYIS31FNELNDLFKA41ACLPLPGYRV
51-10051REITENLMAT61GDLDQDGRIS71FDEFIKIFHG81LKSTDVAKTF91RKAINKKEGI
101-150101CAIGGTSEQS111SVGTQHSYSE121EEKYAFVNWI131NKALENDPDC141RHVIPMNPNT
151-200151NDLFNAVGDG161IVLCKMINLS171VPDTIDERTI181NKKKLTPFTI191QENLNLALNS
201-246201ASAIGCHVVN211IGAEDLKEGK221PYLVLGLLWQ231VIKIGLFADI241ELSRNE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 42 | EF-hand domain pair EF-hand domain | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.93
|
|
| 101 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.85
Deep-Palm: 0.87
|
|
| 140 | - | - | - |
Deep-Palm: 0.07
|
|
| 164 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.64
|
| 206 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
PC3
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 140 | C → C | 0.001887 | SNP | Silent | UCEC |
| 403 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 430 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 479 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 588 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| ? | ? → ? | 0.002506 | SNP | Nonstop Mutation | COAD |